Martin Klima

Prague, PR 16610, Czech Republic

Last Updated: 09/26/2026

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Found 45 publications

Compounds mimicking the Michaelis-Menten transition state of the phosphatidylinositol 4-kinase.

Compounds mimicking the Michaelis-Menten transition state of the phosphatidylinositol 4-kinase.

Journal: Bioorganic & medicinal chemistry

Published: February 20, 2026

Structure of the hibernating Francisella tularensis ribosome and mechanistic insights into its inhibition by antibiotics.

Structure of the hibernating Francisella tularensis ribosome and mechanistic insights into its inhibition by antibiotics.

Journal: Nucleic acids research

Published: December 11, 2025

Phosphatidylinositol transfer protein α binds microcolins in its open conformation.

Phosphatidylinositol transfer protein α binds microcolins in its open conformation.

Journal: Acta crystallographica. Section D, Structural biology

Published: December 04, 2025

Structural mechanism and inhibitor discovery for DhhP, a Borrelia burgdorferi cyclic di-AMP phosphodiesterase with an Fe/Mn bimetallic center.

Structural mechanism and inhibitor discovery for DhhP, a Borrelia burgdorferi cyclic di-AMP phosphodiesterase with an Fe/Mn bimetallic center.

Journal: Structure (London, England : 1993)

Published: November 03, 2025

Structural basis for allosteric regulation of mycobacterial guanosine 5´-monophosphate reductase by ATP and GTP.

Structural basis for allosteric regulation of mycobacterial guanosine 5´-monophosphate reductase by ATP and GTP.

Journal: Nature communications

Published: June 06, 2025

Molecular dynamics of evaporative cooling of water clusters.

Molecular dynamics of evaporative cooling of water clusters.

Journal: Physical chemistry chemical physics : PCCP

Published: December 23, 2024

SPR is a fast and straightforward method to estimate the binding constants of cyclic dinucleotides to their binding partners, such as STING or poxin.

SPR is a fast and straightforward method to estimate the binding constants of cyclic dinucleotides to their binding partners, such as STING or poxin.

Journal: Biophysical chemistry

Published: November 22, 2024

Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39.

Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39.

Journal: Journal of structural biology: X

Published: July 09, 2024

Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors.

Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors.

Journal: bioRxiv : the preprint server for biology

Published: October 24, 2023

Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.

Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.

Journal: Structure (London, England : 1993)

Published: October 02, 2023

Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport.

Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport.

Journal: Cells

Published: July 17, 2023

Properties of water and argon clusters developed in supersonic expansions.

Properties of water and argon clusters developed in supersonic expansions.

Journal: The Journal of chemical physics

Published: July 08, 2023

Showing 1-12 of 45

Last Updated: 09/26/2026