Martine Gehin

Allschwil, BL, Switzerland

Last Updated: 09/26/2026

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Found 20 publications

Effect of Daridorexant on the Pharmacokinetics of Midazolam, and on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Male Subjects.

Effect of Daridorexant on the Pharmacokinetics of Midazolam, and on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Male Subjects.

Journal: Drugs in R&D

Published: January 14, 2024

Clinical pharmacology of selatogrel for self-administration by patients with suspected acute myocardial infarction.

Clinical pharmacology of selatogrel for self-administration by patients with suspected acute myocardial infarction.

Journal: Expert opinion on drug metabolism & toxicology

Published: October 05, 2023

Mind the Gap: Model-Based Switching from Selatogrel to Maintenance Therapy with Oral P2Y12 Receptor Antagonists.

Mind the Gap: Model-Based Switching from Selatogrel to Maintenance Therapy with Oral P2Y12 Receptor Antagonists.

Journal: Biomolecules

Published: July 26, 2023

Pharmacokinetics, pharmacodynamics and safety of the novel C-X-C chemokine receptor 3 antagonist ACT-777991: Results from the first-in-human study in healthy adults.

Pharmacokinetics, pharmacodynamics and safety of the novel C-X-C chemokine receptor 3 antagonist ACT-777991: Results from the first-in-human study in healthy adults.

Journal: British journal of clinical pharmacology

Published: March 17, 2023

Effect of gastric pH and of a moderate CYP3A4 inducer on the pharmacokinetics of daridorexant, a dual orexin receptor antagonist.

Effect of gastric pH and of a moderate CYP3A4 inducer on the pharmacokinetics of daridorexant, a dual orexin receptor antagonist.

Journal: British journal of clinical pharmacology

Published: May 01, 2021

Effect of Renal Function Impairment on the Pharmacokinetics, Safety, and Tolerability of the Iminosugar Sinbaglustat.

Effect of Renal Function Impairment on the Pharmacokinetics, Safety, and Tolerability of the Iminosugar Sinbaglustat.

Journal: Journal of clinical pharmacology

Published: October 21, 2020

Assessment of Target Engagement in a First-in-Human Trial with Sinbaglustat, an Iminosugar to Treat Lysosomal Storage Disorders.

Assessment of Target Engagement in a First-in-Human Trial with Sinbaglustat, an Iminosugar to Treat Lysosomal Storage Disorders.

Journal: Clinical and translational science

Published: July 07, 2020

Pharmacokinetics, pharmacodynamics, tolerability and prediction of clinically effective dose of ACT-774312: A novel CRTH2 antagonist.

Pharmacokinetics, pharmacodynamics, tolerability and prediction of clinically effective dose of ACT-774312: A novel CRTH2 antagonist.

Journal: Basic & clinical pharmacology & toxicology

Published: October 19, 2018

Assessment of Peripheral Serotonin Synthesis Using Stable Isotope-Labeled Tryptophan.

Assessment of Peripheral Serotonin Synthesis Using Stable Isotope-Labeled Tryptophan.

Journal: Clinical pharmacology and therapeutics

Published: December 12, 2017

Pediatric Development of Bosentan Facilitated by Modeling and Simulation.

Pediatric Development of Bosentan Facilitated by Modeling and Simulation.

Journal: Paediatric drugs

Published: January 13, 2017

A bosentan pharmacokinetic study to investigate dosing regimens in paediatric patients with pulmonary arterial hypertension: FUTURE-3.

A bosentan pharmacokinetic study to investigate dosing regimens in paediatric patients with pulmonary arterial hypertension: FUTURE-3.

Journal: British journal of clinical pharmacology

Published: November 10, 2016

Bosentan Pharmacokinetics in Pediatric Patients with Pulmonary Arterial Hypertension: Comparison of Dried Blood Spot and Plasma Analysis.

Bosentan Pharmacokinetics in Pediatric Patients with Pulmonary Arterial Hypertension: Comparison of Dried Blood Spot and Plasma Analysis.

Journal: Pharmacology

Published: April 28, 2016

Showing 1-12 of 20

Last Updated: 09/26/2026