Martine J. Smit

Amsterdam, NH, Netherlands

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 100 publications

Atypical GPCR Activation Resolved by Nanobody Engineering.

Atypical GPCR Activation Resolved by Nanobody Engineering.

Journal: bioRxiv : the preprint server for biology
Published: January 16, 2026

G protein-coupled receptor kinase 3 couples atypical chemokine receptor 4 independent of G proteins.

G protein-coupled receptor kinase 3 couples atypical chemokine receptor 4 independent of G proteins.

Journal: Molecular pharmacology
Published: January 09, 2026

CXCR4-EGFR heteromers show ligand-dependent changes in conformation and signaling.

CXCR4-EGFR heteromers show ligand-dependent changes in conformation and signaling.

Journal: Cell chemical biology
Published: November 14, 2025

Physical interaction with Ephrin B1 promotes CXCR4 intracellular localization and oncogenic potential.

Physical interaction with Ephrin B1 promotes CXCR4 intracellular localization and oncogenic potential.

Journal: Cellular and molecular life sciences : CMLS
Published: July 17, 2025

Plasma membrane rather than endosomal Gq signaling drives transcriptional activity by the viral chemokine receptor US28 in glioblastoma.

Plasma membrane rather than endosomal Gq signaling drives transcriptional activity by the viral chemokine receptor US28 in glioblastoma.

Journal: bioRxiv : the preprint server for biology
Published: July 15, 2025

Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.

Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: June 11, 2025

Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies.

Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies.

Journal: bioRxiv : the preprint server for biology
Published: November 22, 2024

Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies.

Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies.

Journal: Nature communications
Published: November 04, 2024

Signal termination of the chemokine receptor CCR9 is governed by an arrestin-independent phosphorylation mechanism.

Signal termination of the chemokine receptor CCR9 is governed by an arrestin-independent phosphorylation mechanism.

Journal: The Journal of biological chemistry
Published: November 01, 2024

Presentation of CXCL12γ by heparan sulfate proteoglycans activates CXCR4 without desensitization in normal and malignant B cells.

Presentation of CXCL12γ by heparan sulfate proteoglycans activates CXCR4 without desensitization in normal and malignant B cells.

Journal: Blood advances
Published: July 31, 2024

Pharmacological characterization of a clinical candidate, TG-0054, a small molecule inverse agonist targeting CXCR4.

Pharmacological characterization of a clinical candidate, TG-0054, a small molecule inverse agonist targeting CXCR4.

Journal: Molecular pharmacology
Published: July 08, 2024

Multivalent CXCR4-targeting nanobody formats differently affect affinity, receptor clustering, and antagonism.

Multivalent CXCR4-targeting nanobody formats differently affect affinity, receptor clustering, and antagonism.

Journal: Biochemical pharmacology
Published: April 10, 2024
Showing 1-12 of 100

Last Updated: 09/26/2026