Marzena Mazur

Warsaw, MZ 02089, Poland

Last Updated: 09/26/2026

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Found 17 publications

Structure-Guided Discovery of OAT-4828 as Potent, Selective, and Orally Bioavailable USP7 Inhibitor with In Vivo Antileukemic Activity.

Structure-Guided Discovery of OAT-4828 as Potent, Selective, and Orally Bioavailable USP7 Inhibitor with In Vivo Antileukemic Activity.

Journal: Journal of medicinal chemistry

Published: May 06, 2026

Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: implications for the involvement of pirin.

Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: implications for the involvement of pirin.

Journal: Frontiers in pharmacology

Published: October 01, 2024

Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1.

Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1.

Journal: Journal of medicinal chemistry

Published: March 01, 2024

Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma.

Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma.

Journal: International journal of molecular sciences

Published: January 23, 2023

The Anti-Inflammatory Effect of Acidic Mammalian Chitinase Inhibitor OAT-177 in DSS-Induced Mouse Model of Colitis.

The Anti-Inflammatory Effect of Acidic Mammalian Chitinase Inhibitor OAT-177 in DSS-Induced Mouse Model of Colitis.

Journal: International journal of molecular sciences

Published: January 18, 2022

Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis.

Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis.

Journal: European journal of pharmacology

Published: September 02, 2021

Chitinases and Chitinase-Like Proteins as Therapeutic Targets in Inflammatory Diseases, with a Special Focus on Inflammatory Bowel Diseases.

Chitinases and Chitinase-Like Proteins as Therapeutic Targets in Inflammatory Diseases, with a Special Focus on Inflammatory Bowel Diseases.

Journal: International journal of molecular sciences

Published: April 27, 2021

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.

Journal: Journal of medicinal chemistry

Published: October 20, 2020

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase.

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase.

Journal: ACS medicinal chemistry letters

Published: February 21, 2020

Cyclic derivatives of morphiceptin possess anti-transit effect in the gastrointestinal tract and alleviate abdominal pain in mice.

Cyclic derivatives of morphiceptin possess anti-transit effect in the gastrointestinal tract and alleviate abdominal pain in mice.

Journal: Pharmacological reports : PR

Published: November 21, 2019

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases.

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases.

Journal: Journal of medicinal chemistry

Published: July 11, 2019

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.

Journal: Journal of medicinal chemistry

Published: December 29, 2017

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Last Updated: 09/26/2026