Masahiko Takahashi

Niigata, Japan

Last Updated: 09/26/2026

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Found 25 publications

Targeting Ubiquitinated Protein Aggregates in Neurodegenerative Diseases: current Status and Future Directions.

Targeting Ubiquitinated Protein Aggregates in Neurodegenerative Diseases: current Status and Future Directions.

Journal: Molecular and cellular biology
Published: August 04, 2026

Dual Regulatory Roles of USP10 in Tau Pathology and Neuronal Fate During Alzheimer's Disease Progression.

Dual Regulatory Roles of USP10 in Tau Pathology and Neuronal Fate During Alzheimer's Disease Progression.

Journal: Molecular and cellular biology
Published: December 09, 2025

Downregulation of the deubiquitinating enzyme USP10 correlates with neuronal apoptosis in HTLV-1-associated myelopathy.

Downregulation of the deubiquitinating enzyme USP10 correlates with neuronal apoptosis in HTLV-1-associated myelopathy.

Journal: Scientific reports
Published: September 01, 2025

USP10 inhibits the degradation of α-synuclein, a pathogenic factor associated with Parkinson's disease, by inhibiting chaperone-mediated autophagy.

USP10 inhibits the degradation of α-synuclein, a pathogenic factor associated with Parkinson's disease, by inhibiting chaperone-mediated autophagy.

Journal: The Journal of biological chemistry
Published: November 16, 2024

TDP-43 mutants with different aggregation properties exhibit distinct toxicity, axonal transport, and secretion for disease progression in a mouse ALS/FTLD model.

TDP-43 mutants with different aggregation properties exhibit distinct toxicity, axonal transport, and secretion for disease progression in a mouse ALS/FTLD model.

Journal: Neurobiology of disease
Published: October 25, 2024

USP10 Inhibits Aberrant Cytoplasmic Aggregation of TDP-43 by Promoting Stress Granule Clearance.

USP10 Inhibits Aberrant Cytoplasmic Aggregation of TDP-43 by Promoting Stress Granule Clearance.

Journal: Molecular and cellular biology
Published: January 10, 2022

USP10 inhibits the dopamine-induced reactive oxygen species-dependent apoptosis of neuronal cells by stimulating the antioxidant Nrf2 activity.

USP10 inhibits the dopamine-induced reactive oxygen species-dependent apoptosis of neuronal cells by stimulating the antioxidant Nrf2 activity.

Journal: The Journal of biological chemistry
Published: May 12, 2021

Myeloid-associated differentiation marker is an essential host factor for human parechovirus PeV-A3 entry.

Myeloid-associated differentiation marker is an essential host factor for human parechovirus PeV-A3 entry.

Journal: Nature communications
Published: April 11, 2021

Antitumor Effect of Sugar-Modified Cytosine Nucleosides on Growth of Adult T-Cell Leukemia Cells in Mice.

Antitumor Effect of Sugar-Modified Cytosine Nucleosides on Growth of Adult T-Cell Leukemia Cells in Mice.

Journal: Vaccines
Published: October 15, 2020

The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-43.

The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-43.

Journal: iScience
Published: September 10, 2020

G3BP1 inhibits ubiquitinated protein aggregations induced by p62 and USP10.

G3BP1 inhibits ubiquitinated protein aggregations induced by p62 and USP10.

Journal: Scientific reports
Published: February 19, 2019

USP10 is a critical factor for Tau-positive stress granule formation in neuronal cells.

USP10 is a critical factor for Tau-positive stress granule formation in neuronal cells.

Journal: Scientific reports
Published: December 31, 2018
Showing 1-12 of 25

Last Updated: 09/26/2026