Masahiro Hiratsuka

Sendai, 9808574, Japan

Last Updated: 09/26/2026

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Found 110 publications

Effect of Cytochrome P450 3A4 Genetic Polymorphisms on Heme Recognition by Using Molecular Dynamics Simulations.

Effect of Cytochrome P450 3A4 Genetic Polymorphisms on Heme Recognition by Using Molecular Dynamics Simulations.

Journal: Biological & pharmaceutical bulletin

Published: March 29, 2026

A rare variant in DPYD c.812delT causes severe adverse events of S-1 in a patient with tongue cancer.

A rare variant in DPYD c.812delT causes severe adverse events of S-1 in a patient with tongue cancer.

Journal: Cancer chemotherapy and pharmacology

Published: March 13, 2026

Differences in reactive metabolite formation and cytochrome P450 binding between acetaminophen and its bicyclo[1.1.1]pentane bioisostere.

Differences in reactive metabolite formation and cytochrome P450 binding between acetaminophen and its bicyclo[1.1.1]pentane bioisostere.

Journal: Drug metabolism and pharmacokinetics

Published: January 15, 2026

UDP-glucuronosyltransferase 1A9 function is mediated by the two C-terminal lysine residues and proper mobility/flexibility of the cytoplasmic tail.

UDP-glucuronosyltransferase 1A9 function is mediated by the two C-terminal lysine residues and proper mobility/flexibility of the cytoplasmic tail.

Journal: Biochemical and biophysical research communications

Published: November 10, 2025

In Silico Binary Classification of Catalytic Function (Unaffected or Impaired) of Flavin-Containing Monooxygenase 3 (FMO3) Variants and in Vitro Validation Using New Variants Found in a Japanese Genome Resource Database.

In Silico Binary Classification of Catalytic Function (Unaffected or Impaired) of Flavin-Containing Monooxygenase 3 (FMO3) Variants and in Vitro Validation Using New Variants Found in a Japanese Genome Resource Database.

Journal: Biological & pharmaceutical bulletin

Published: July 21, 2025

Comprehensive functional characterization of rare and known CYP2E1 allelic variants identified in a Japanese population.

Comprehensive functional characterization of rare and known CYP2E1 allelic variants identified in a Japanese population.

Journal: Biochemical pharmacology

Published: June 24, 2025

Evaluation of the functional impact of rare CYP2C19 missense variants identified in understudied Populations: An Integrated in silico and in vitro analysis.

Evaluation of the functional impact of rare CYP2C19 missense variants identified in understudied Populations: An Integrated in silico and in vitro analysis.

Journal: Biochemical pharmacology

Published: June 11, 2025

Disulfide bond-mediated stabilization of the oligomers of UDP-glucuronosyltransferase 2B7.

Disulfide bond-mediated stabilization of the oligomers of UDP-glucuronosyltransferase 2B7.

Journal: The Journal of biological chemistry

Published: May 01, 2025

Effect of Organic Anion Transporting Polypeptide 1B1 on Plasma Concentration Dynamics of Clozapine in Patients with Treatment-Resistant Schizophrenia.

Effect of Organic Anion Transporting Polypeptide 1B1 on Plasma Concentration Dynamics of Clozapine in Patients with Treatment-Resistant Schizophrenia.

Journal: International journal of molecular sciences

Published: November 20, 2024

Carbon-Based Particles Inhibit Antigen Penetration Into the Skin by Adsorbing the Antigen.

Carbon-Based Particles Inhibit Antigen Penetration Into the Skin by Adsorbing the Antigen.

Journal: Experimental dermatology

Published: September 24, 2024

Functional significance of CYP2B6 gene rare allelic variants identified in Japanese individuals.

Functional significance of CYP2B6 gene rare allelic variants identified in Japanese individuals.

Journal: Biochemical pharmacology

Published: May 06, 2024

Genetic variation present in the CYP3A4 gene in Ni-Vanuatu and Kenyan populations in malaria endemicity.

Genetic variation present in the CYP3A4 gene in Ni-Vanuatu and Kenyan populations in malaria endemicity.

Journal: Drug metabolism and pharmacokinetics

Published: April 11, 2024

Showing 1-12 of 110

Last Updated: 09/26/2026