Masakazu Fukushima
Tokushima, Japan
Last Updated: 09/26/2026
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Found 13 publications
A novel intraperitoneal therapy for gastric cancer with DFP-10825, a unique RNAi therapeutic targeting thymidylate synthase, in a peritoneally disseminated xenograft model.
Journal: Cancer medicine
Published: July 14, 2019
A simplified method for manufacturing RNAi therapeutics for local administration.
Journal: International journal of pharmaceutics
Published: February 19, 2019
Anticancer activity of the intraperitoneal-delivered DFP-10825, the cationic liposome-conjugated RNAi molecule targeting thymidylate synthase, on peritoneal disseminated ovarian cancer xenograft model.
Journal: Drug design, development and therapy
Published: April 11, 2018
Analysis of the prolonged infusion of DFP-10917, a deoxycytidine analog, as a therapeutic strategy for the treatment of human tumor xenografts in vivo.
Journal: International journal of oncology
Published: July 07, 2017
Development of new promising antimetabolite, DFP-11207 with self-controlled toxicity in rodents.
Journal: Drug design, development and therapy
Published: June 28, 2017
Role of the uridine/cytidine kinase 2 mutation in cellular sensitiveness toward 3'-ethynylcytidine treatment of human cancer cells.
Journal: Anti-cancer drugs
Published: May 26, 2017
Systemically Administered RNAi Molecule Sensitizes Malignant Pleural Mesotheliomal Cells to Pemetrexed Therapy.
Journal: Molecular pharmaceutics
Published: October 15, 2016
Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model.
Journal: Cancer letters
Published: September 20, 2016
Co-administration of liposomal l-OHP and PEGylated TS shRNA-lipoplex: A novel approach to enhance anti-tumor efficacy and reduce the immunogenic response to RNAi molecules.
Journal: Journal of controlled release : official journal of the Controlled Release Society
Published: August 04, 2016
Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model.
Journal: International journal of oncology
Published: December 01, 2015
Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis.
Journal: International journal of molecular medicine
Published: July 22, 2015
Last Updated: 09/26/2026