Mate Gyimesi

Budapest, BU 1015, Hungary

Last Updated: 09/26/2026

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Found 17 publications

Fragment-based structure-activity relationship analysis of CK-571 reveals non-interacting groups drive smooth muscle myosin selectivity.

Fragment-based structure-activity relationship analysis of CK-571 reveals non-interacting groups drive smooth muscle myosin selectivity.

Journal: European journal of medicinal chemistry

Published: June 27, 2025

Comprehensive SAR analysis of actomyolytics, drug candidates targeting the actomyosin complex.

Comprehensive SAR analysis of actomyolytics, drug candidates targeting the actomyosin complex.

Journal: European journal of medicinal chemistry

Published: May 22, 2025

Chiral HPLC separation of enantiomeric blebbistatin derivatives and racemization analysis in vertebrate tissues.

Chiral HPLC separation of enantiomeric blebbistatin derivatives and racemization analysis in vertebrate tissues.

Journal: Journal of pharmaceutical and biomedical analysis

Published: April 16, 2021

Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2.

Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2.

Journal: The Journal of pharmacology and experimental therapeutics

Published: June 15, 2020

Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness.

Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness.

Journal: Cell

Published: May 23, 2020

Direct myosin-2 inhibition enhances cerebral perfusion resulting in functional improvement after ischemic stroke.

Direct myosin-2 inhibition enhances cerebral perfusion resulting in functional improvement after ischemic stroke.

Journal: Theranostics

Published: November 13, 2019

The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom's syndrome helicase for efficient disruption of D-loops.

The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom's syndrome helicase for efficient disruption of D-loops.

Journal: Nature communications

Published: February 26, 2019

Targeting Myosin by Blebbistatin Derivatives: Optimization and Pharmacological Potential.

Targeting Myosin by Blebbistatin Derivatives: Optimization and Pharmacological Potential.

Journal: Trends in biochemical sciences

Published: April 26, 2018

Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion.

Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion.

Journal: Scientific reports

Published: October 13, 2017

Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state.

Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state.

Journal: Nucleic acids research

Published: October 06, 2017

RecQ helicase triggers a binding mode change in the SSB-DNA complex to efficiently initiate DNA unwinding.

RecQ helicase triggers a binding mode change in the SSB-DNA complex to efficiently initiate DNA unwinding.

Journal: Nucleic acids research

Published: May 23, 2017

Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination.

Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: January 11, 2017

Showing 1-12 of 17

Last Updated: 09/26/2026