Mathias Cobbaut
1 Midland Road
London, ENG, United Kingdom
London, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 17 publications
The chordoid glioma PRKCA D463H mutation is a kinase inactive, gain-of-function allele that induces early-onset chondrosarcoma in mice.
Journal: Science signaling
Published: November 04, 2025
Lessons in conformational signalling: non-catalytic functions of protein kinase C isozymes.
Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Published: April 07, 2025
Capture, mutual inhibition and release mechanism for aPKC-Par6 and its multisite polarity substrate Lgl.
Journal: Nature structural & molecular biology
Published: January 30, 2024
A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease.
Journal: Nature communications
Published: November 22, 2023
Into the fold: advances in understanding aPKC membrane dynamics.
Journal: The Biochemical journal
Published: September 14, 2023
Control of atypical PKCι membrane dissociation by tyrosine phosphorylation within a PB1-C1 interdomain interface.
Journal: The Journal of biological chemistry
Published: January 13, 2023
Genome-Protective Topoisomerase 2a-Dependent G2 Arrest Requires p53 in hTERT-Positive Cancer Cells.
Journal: Cancer research
Published: June 03, 2021
Equivocal, explicit and emergent actions of PKC isoforms in cancer.
Journal: Nature reviews. Cancer
Published: October 02, 2020
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyrimidine-based protein kinase D inhibitors.
Journal: European journal of medicinal chemistry
Published: March 06, 2020
The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity.
Journal: Journal of cell science
Published: August 09, 2018
Last Updated: 09/26/2026