Mathias Wenes
Geneve, GE, Switzerland
Last Updated: 09/26/2026
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Found 22 publications
The PI3Kδ inhibitor roginolisib (IOA-244) preserves T-cell function and activity.
Journal: Molecular oncology
Published: September 01, 2025
A novel mitochondrial pyruvate carrier inhibitor drives stem cell-like memory CAR T cell generation and enhances antitumor efficacy.
Journal: Molecular therapy. Oncology
Published: March 14, 2024
Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy.
Journal: Nature cancer
Published: March 17, 2023
IOA-244 is a Non-ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance.
Journal: Cancer research communications
Published: November 22, 2022
Efficacy and safety of universal (TCRKO) ARI-0001 CAR-T cells for the treatment of B-cell lymphoma.
Journal: Frontiers in immunology
Published: August 04, 2022
Reductive carboxylation epigenetically instructs T cell differentiation.
Journal: Nature
Published: January 08, 2022
The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function.
Journal: Cell metabolism
Published: September 28, 2021
Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity.
Journal: Nature immunology
Published: February 27, 2021
Assessment of memory formation by metabolically engineered antigen-specific CD8 T cells.
Journal: Methods in enzymology
Published: January 18, 2020
Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity.
Journal: Cellular & molecular immunology
Published: July 03, 2019
Navigating metabolic pathways to enhance antitumour immunity and immunotherapy.
Journal: Nature reviews. Clinical oncology
Published: March 28, 2019
Last Updated: 09/26/2026