Matteo Sebastiano-Rossi
Turin, 10126, Italy
Last Updated: 09/26/2026
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Found 15 publications
MK4 Repositioning for IAHSP: Overcoming In Vivo Data Gaps through In Silico Refinement and In Vitro Validation.
Journal: ACS chemical neuroscience
Published: February 09, 2026
BBB-Permeable PROTACs: Where Do We Stand?
Journal: ACS medicinal chemistry letters
Published: December 22, 2025
Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target-Driven Drug Discovery.
Journal: Medicinal research reviews
Published: April 23, 2025
Restoring adapter protein complex 4 function with small molecules: an in silico approach to spastic paraplegia 50.
Journal: Protein science : a publication of the Protein Society
Published: August 03, 2024
IMHB-Mediated Chameleonicity in Drug Design: A Focus on Structurally Related PROTACs.
Journal: Journal of medicinal chemistry
Published: June 29, 2024
DNA methylation analysis in patients with neurodevelopmental disorders improves variant interpretation and reveals complexity.
Journal: HGG advances
Published: December 06, 2023
DegraderTCM: A Computationally Sparing Approach for Predicting Ternary Degradation Complexes.
Journal: ACS medicinal chemistry letters
Published: August 16, 2023
Chamelogk: A Chromatographic Chameleonicity Quantifier to Design Orally Bioavailable Beyond-Rule-of-5 Drugs.
Journal: Journal of medicinal chemistry
Published: July 25, 2023
Spinocerebellar ataxia 38: structure-function analysis shows ELOVL5 G230V is proteotoxic, conformationally altered and a mutational hotspot.
Journal: Human genetics
Published: February 22, 2023
Conformational Sampling Deciphers the Chameleonic Properties of a VHL-Based Degrader.
Journal: Pharmaceutics
Published: December 19, 2022
Personalized Treatment for Infantile Ascending Hereditary Spastic Paralysis Based on In Silico Strategies.
Journal: Molecules (Basel, Switzerland)
Published: October 03, 2022
Refinement of Computational Access to Molecular Physicochemical Properties: From Ro5 to bRo5.
Journal: Journal of medicinal chemistry
Published: September 12, 2022
Last Updated: 09/26/2026