Matthaus Getlik

Dortmund, NW 44227, Germany

Last Updated: 09/26/2026

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Found 11 publications

An Unusual Intramolecular Halogen Bond Guides Conformational Selection.

An Unusual Intramolecular Halogen Bond Guides Conformational Selection.

Journal: Angewandte Chemie (International ed. in English)

Published: April 27, 2018

Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.

Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.

Journal: Cell reports

Published: February 17, 2017

Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1).

Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1).

Journal: Journal of medicinal chemistry

Published: March 10, 2016

Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

Journal: Nature chemical biology

Published: September 18, 2015

Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach.

Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach.

Journal: Journal of medicinal chemistry

Published: August 15, 2015

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

Journal: Nature chemical biology

Published: October 20, 2014

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.

Journal: Nature

Published: June 24, 2014

Targeting gain of function and resistance mutations in Abl and KIT by hybrid compound design.

Targeting gain of function and resistance mutations in Abl and KIT by hybrid compound design.

Journal: Journal of medicinal chemistry

Published: June 19, 2013

Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction.

Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction.

Journal: ACS medicinal chemistry letters

Published: December 20, 2012

Targeting GSK3 from Ustilago maydis: type-II kinase inhibitors as potential antifungals.

Targeting GSK3 from Ustilago maydis: type-II kinase inhibitors as potential antifungals.

Journal: ACS chemical biology

Published: May 02, 2012

Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38α kinase.

Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38α kinase.

Journal: PloS one

Published: May 01, 2012

Showing 1-11 of 11

Last Updated: 09/26/2026