Matthew H. Taylor-Bridgland

AstraZeneca R&D
Macclesfield, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 10 publications

Mutations of the nACh Receptor M4 Helix Reveal Different Phenotypes in Different Expression Systems: Could Lipids be Responsible?

Mutations of the nACh Receptor M4 Helix Reveal Different Phenotypes in Different Expression Systems: Could Lipids be Responsible?

Journal: Frontiers in physiology

Published: January 08, 2022

Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.

Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.

Journal: Scientific reports

Published: July 16, 2020

Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].

Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].

Journal: Toxicology and applied pharmacology

Published: April 06, 2020

Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.

Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.

Journal: Scientific reports

Published: December 19, 2019

A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.

A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.

Journal: Toxicology and applied pharmacology

Published: November 13, 2019

A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm.

A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm.

Journal: Journal of biomolecular screening

Published: April 07, 2015

Evaluation of drug-induced QT interval prolongation in animal and human studies: a literature review of concordance.

Evaluation of drug-induced QT interval prolongation in animal and human studies: a literature review of concordance.

Journal: British journal of pharmacology

Published: December 07, 2014

Prediction of Thorough QT study results using action potential simulations based on ion channel screens.

Prediction of Thorough QT study results using action potential simulations based on ion channel screens.

Journal: Journal of pharmacological and toxicological methods

Published: March 26, 2014

Predicting changes in cardiac myocyte contractility during early drug discovery with in vitro assays.

Predicting changes in cardiac myocyte contractility during early drug discovery with in vitro assays.

Journal: Toxicology and applied pharmacology

Published: February 04, 2014

Pharmacological and electrophysiological characterization of AZSMO-23, an activator of the hERG K(+) channel.

Pharmacological and electrophysiological characterization of AZSMO-23, an activator of the hERG K(+) channel.

Journal: British journal of pharmacology

Published: January 22, 2014

Showing 1-10 of 10

Last Updated: 09/26/2026