Matthew Leibovitch

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 15 publications

WEE1 inhibitors trigger GCN2-mediated activation of the integrated stress response.

WEE1 inhibitors trigger GCN2-mediated activation of the integrated stress response.

Journal: Nature communications
Published: March 11, 2025

Nanoparticle encapsulation enables systemic IGF-Trap delivery to inhibit intracerebral glioma growth.

Nanoparticle encapsulation enables systemic IGF-Trap delivery to inhibit intracerebral glioma growth.

Journal: Neuro-oncology
Published: January 29, 2025

Blocking tumor-intrinsic MNK1 kinase restricts metabolic adaptation and diminishes liver metastasis.

Blocking tumor-intrinsic MNK1 kinase restricts metabolic adaptation and diminishes liver metastasis.

Journal: Science advances
Published: September 13, 2024

Targeting the IGF-Axis in Cultured Pediatric High-Grade Glioma Cells Inhibits Cell Cycle Progression and Survival.

Targeting the IGF-Axis in Cultured Pediatric High-Grade Glioma Cells Inhibits Cell Cycle Progression and Survival.

Journal: Pharmaceuticals (Basel, Switzerland)
Published: January 01, 2023

Identification of a Resistance Mechanism to IGF-IR Targeting in Human Triple Negative MDA-MB-231 Breast Cancer Cells.

Identification of a Resistance Mechanism to IGF-IR Targeting in Human Triple Negative MDA-MB-231 Breast Cancer Cells.

Journal: Biomolecules
Published: December 17, 2020

Reprogramming of Nucleotide Metabolism Mediates Synergy between Epigenetic Therapy and MAP Kinase Inhibition.

Reprogramming of Nucleotide Metabolism Mediates Synergy between Epigenetic Therapy and MAP Kinase Inhibition.

Journal: Molecular cancer therapeutics
Published: April 02, 2020

Translational control of breast cancer plasticity.

Translational control of breast cancer plasticity.

Journal: Nature communications
Published: March 20, 2019

Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression.

Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression.

Journal: The EMBO journal
Published: December 10, 2018

Analysis of the pathogenic I326T variant of human tRNA nucleotidyltransferase reveals reduced catalytic activity and thermal stability in vitro linked to a conformational change.

Analysis of the pathogenic I326T variant of human tRNA nucleotidyltransferase reveals reduced catalytic activity and thermal stability in vitro linked to a conformational change.

Journal: Biochimica et biophysica acta. Proteins and proteomics
Published: October 12, 2018

An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis.

An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis.

Journal: Nature communications
Published: August 23, 2018

In vitro studies of disease-linked variants of human tRNA nucleotidyltransferase reveal decreased thermal stability and altered catalytic activity.

In vitro studies of disease-linked variants of human tRNA nucleotidyltransferase reveal decreased thermal stability and altered catalytic activity.

Journal: Biochimica et biophysica acta. Proteins and proteomics
Published: November 17, 2017

Dysregulation of mRNA translation and energy metabolism in cancer.

Dysregulation of mRNA translation and energy metabolism in cancer.

Journal: Advances in biological regulation
Published: October 11, 2017
Showing 1-12 of 15

Last Updated: 09/26/2026