Matthias C. Witschel

Carl Bosch Str. 38
Ludwigshafen Am Rhein, RP 67056, Germany

Last Updated: 09/26/2026

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Found 28 publications

The Mycobacterial cyt-bc1:aac3 Oxidase as a Drug Target: Activities of Arylvinylpiperazine Amides and Aminoquinazolines against Mycobacterium ulcerans.

The Mycobacterial cyt-bc1:aac3 Oxidase as a Drug Target: Activities of Arylvinylpiperazine Amides and Aminoquinazolines against Mycobacterium ulcerans.

Journal: Journal of medicinal chemistry

Published: July 14, 2026

Targeting the Energy-Coupling Factor Transporters: A Novel Antibiotic Drug Target in Streptococcus pneumoniae.

Targeting the Energy-Coupling Factor Transporters: A Novel Antibiotic Drug Target in Streptococcus pneumoniae.

Journal: Journal of medicinal chemistry

Published: June 12, 2026

A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum.

A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum.

Journal: Angewandte Chemie (International ed. in English)

Published: June 27, 2025

Targeting Plasmodium falciparum IspD in the Methyl-d-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity.

Targeting Plasmodium falciparum IspD in the Methyl-d-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity.

Journal: Journal of medicinal chemistry

Published: September 20, 2024

Agrochemical Lessons for Infectious Disease Research: New Resistance Breaking Antifungal Hits against Candida auris.

Agrochemical Lessons for Infectious Disease Research: New Resistance Breaking Antifungal Hits against Candida auris.

Journal: ACS medicinal chemistry letters

Published: November 29, 2022

Selective killing of the human gastric pathogen Helicobacter pylori by mitochondrial respiratory complex I inhibitors.

Selective killing of the human gastric pathogen Helicobacter pylori by mitochondrial respiratory complex I inhibitors.

Journal: Cell chemical biology

Published: September 22, 2022

Inhibition profile of trifludimoxazin towards PPO2 target site mutations.

Inhibition profile of trifludimoxazin towards PPO2 target site mutations.

Journal: Pest management science

Published: June 05, 2022

Inhibition of acyl-ACP thioesterase as site of action of the commercial herbicides cumyluron, oxaziclomefone, bromobutide, methyldymron and tebutam.

Inhibition of acyl-ACP thioesterase as site of action of the commercial herbicides cumyluron, oxaziclomefone, bromobutide, methyldymron and tebutam.

Journal: Pest management science

Published: February 15, 2022

Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class.

Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class.

Journal: ChemMedChem

Published: October 26, 2021

Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity.

Search for the Active Ingredients from a 2-Aminothiazole DMSO Stock Solution with Antimalarial Activity.

Journal: ChemMedChem

Published: January 26, 2021

Assessment of the rules related to gaining activity against Gram-negative bacteria.

Assessment of the rules related to gaining activity against Gram-negative bacteria.

Journal: RSC medicinal chemistry

Published: December 04, 2020

Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer.

Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer.

Journal: Nature communications

Published: October 21, 2018

Showing 1-12 of 28

Last Updated: 09/26/2026