Matthias Klugmann

Birkendorfer Str. 65
Biberach An Der Riss, BW 88397, Germany

Last Updated: 09/26/2026

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Found 60 publications

Engineering aptamer dimers (apdimers) for optimization of synthetic riboswitches.

Engineering aptamer dimers (apdimers) for optimization of synthetic riboswitches.

Journal: Nucleic acids research

Published: March 31, 2026

Small Molecule-Controlled Gene Expression: Design of Drug-like High-Affinity Modulators of a Custom-Made Riboswitch.

Small Molecule-Controlled Gene Expression: Design of Drug-like High-Affinity Modulators of a Custom-Made Riboswitch.

Journal: ACS chemical biology

Published: January 05, 2026

Spatial mapping of barcoded, brain-tropic AAVs using multiplexed RNA in situ hybridization.

Spatial mapping of barcoded, brain-tropic AAVs using multiplexed RNA in situ hybridization.

Journal: Molecular therapy. Advances

Published: September 26, 2025

Preclinical development of TAK-754, a high-performance AAV8-based vector expressing coagulation factor VIII.

Preclinical development of TAK-754, a high-performance AAV8-based vector expressing coagulation factor VIII.

Journal: Molecular therapy. Methods & clinical development

Published: August 30, 2024

Vector-Free Deep Tissue Targeting of DNA/RNA Therapeutics via Single Capacitive Discharge Conductivity-Clamped Gene Electrotransfer.

Vector-Free Deep Tissue Targeting of DNA/RNA Therapeutics via Single Capacitive Discharge Conductivity-Clamped Gene Electrotransfer.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: June 13, 2024

Engineering oxypurinol-responsive riboswitches based on bacterial xanthine aptamers for gene expression control in mammalian cell culture.

Engineering oxypurinol-responsive riboswitches based on bacterial xanthine aptamers for gene expression control in mammalian cell culture.

Journal: Nucleic acids research

Published: May 15, 2024

Gene Electrotransfer via Conductivity-Clamped Electric Field Focusing Pivots Sensori-Motor DNA Therapeutics: "A Spoonful of Sugar Helps the Medicine Go Down".

Gene Electrotransfer via Conductivity-Clamped Electric Field Focusing Pivots Sensori-Motor DNA Therapeutics: "A Spoonful of Sugar Helps the Medicine Go Down".

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: February 06, 2024

Riboswitch-controlled IL-12 gene therapy reduces hepatocellular cancer in mice.

Riboswitch-controlled IL-12 gene therapy reduces hepatocellular cancer in mice.

Journal: Frontiers in immunology

Published: December 22, 2023

TRPC Channels Activated by G Protein-Coupled Receptors Drive Ca2+ Dysregulation Leading to Secondary Brain Injury in the Mouse Model.

TRPC Channels Activated by G Protein-Coupled Receptors Drive Ca2+ Dysregulation Leading to Secondary Brain Injury in the Mouse Model.

Journal: Translational stroke research

Published: May 03, 2023

Recessive aminoacyl-tRNA synthetase disorders: lessons learned from in vivo disease models.

Recessive aminoacyl-tRNA synthetase disorders: lessons learned from in vivo disease models.

Journal: Frontiers in neuroscience

Published: March 09, 2023

Dominant aminoacyl-tRNA synthetase disorders: lessons learned from in vivo disease models.

Dominant aminoacyl-tRNA synthetase disorders: lessons learned from in vivo disease models.

Journal: Frontiers in neuroscience

Published: March 09, 2023

Dual-function AAV gene therapy reverses late-stage Canavan disease pathology in mice.

Dual-function AAV gene therapy reverses late-stage Canavan disease pathology in mice.

Journal: Frontiers in molecular neuroscience

Published: October 04, 2022

Showing 1-12 of 60

Last Updated: 09/26/2026