Matthias P. Wymann
Basel, BS, Switzerland
Last Updated: 09/26/2026
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Found 51 publications
A conserved VPS34-PIKfyve-TRPML1-myosin II axis regulates the speed of amoeboid cell migration.
Journal: EMBO reports
Published: December 01, 2025
Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling.
Journal: Chemical science
Published: August 14, 2024
PI3Kγ signaling controls trafficking of CD8+ T cells between lymphoid and non-lymphoid organs and drives hypertension in a murine model.
Journal: Nature communications
Published: July 23, 2024
Specific Requirement of the p84/p110γ Complex of PI3Kγ for Antibody-Activated, Inducible Cross-Presentation in Murine Type 2 DCs.
Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: January 31, 2024
Dual targeting of PI3Kγ and STING overcomes regulatory B cell- and myeloid cell-driven immune suppression in pancreatic cancer.
Journal: Nature cancer
Published: January 09, 2024
A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα.
Journal: Chemical science
Published: September 01, 2023
PI3Kγ in B cells promotes antibody responses and generation of antibody-secreting cells.
Journal: Nature immunology
Published: July 06, 2023
Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor.
Journal: European journal of medicinal chemistry
Published: September 28, 2022
Two-drug trick to target the brain blocks toxicity in the body.
Journal: Nature
Published: September 14, 2022
The role of PI3Kγ in the immune system: new insights and translational implications.
Journal: Nature reviews. Immunology
Published: February 21, 2022
Last Updated: 09/26/2026