Matthijs M. Moerland

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 94 publications

Lost and found in translation: the value of the human imiquimod model.

Lost and found in translation: the value of the human imiquimod model.

Journal: British journal of clinical pharmacology

Published: April 02, 2026

Characterization of the Immune Response after Oral Cholera Vaccination (OCV) and Effects of Mycophenolate Mofetil on Priming of this Immune Response-A Randomized, Placebo-Controlled Trial.

Characterization of the Immune Response after Oral Cholera Vaccination (OCV) and Effects of Mycophenolate Mofetil on Priming of this Immune Response-A Randomized, Placebo-Controlled Trial.

Journal: Clinical pharmacology and therapeutics

Published: March 23, 2026

First-In-Human Safety, Pharmacokinetics, and Pharmacodynamics of VENT-02 Freebase, a CNS-Penetrant NLRP3 Inhibitor.

First-In-Human Safety, Pharmacokinetics, and Pharmacodynamics of VENT-02 Freebase, a CNS-Penetrant NLRP3 Inhibitor.

Journal: Clinical and translational science

Published: February 19, 2026

Interpretation of Chemistry, Hematology and Coagulation Laboratory Results in Early-Phase Clinical Pharmacology Trials; a Retrospective Analysis Based on the Placebo Arm of Randomized-Controlled Trials.

Interpretation of Chemistry, Hematology and Coagulation Laboratory Results in Early-Phase Clinical Pharmacology Trials; a Retrospective Analysis Based on the Placebo Arm of Randomized-Controlled Trials.

Journal: Clinical and translational science

Published: February 09, 2026

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early-Phase Oncology Drug Development.

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early-Phase Oncology Drug Development.

Journal: Clinical pharmacology and therapeutics

Published: December 20, 2025

Early immune responses to intradermal lipopolysaccharide in healthy volunteers: prednisolone's impact on TLR4-mediated inflammation.

Early immune responses to intradermal lipopolysaccharide in healthy volunteers: prednisolone's impact on TLR4-mediated inflammation.

Journal: Frontiers in immunology

Published: October 14, 2025

Neoantigen immune responses in healthy volunteers: insights from multiple integrated keyhole limpet hemocyanin challenge studies on repeated immunization and response covariates.

Neoantigen immune responses in healthy volunteers: insights from multiple integrated keyhole limpet hemocyanin challenge studies on repeated immunization and response covariates.

Journal: Frontiers in pharmacology

Published: October 01, 2025

Translating in vitro gut microbiota models to human context: compositional correlations under dietary fiber intervention.

Translating in vitro gut microbiota models to human context: compositional correlations under dietary fiber intervention.

Journal: Frontiers in microbiology

Published: September 19, 2025

POLB 001, a p38 MAPK inhibitor, decreases local and systemic inflammatory responses following in vivo LPS administration in healthy volunteers: a randomised, double-blind, placebo-controlled study.

POLB 001, a p38 MAPK inhibitor, decreases local and systemic inflammatory responses following in vivo LPS administration in healthy volunteers: a randomised, double-blind, placebo-controlled study.

Journal: Frontiers in immunology

Published: August 12, 2025

Breaking Barriers: Characterization of the Intradermal Lipopolysaccharide Challenge as an In Vivo Model for Controlled Induction of Vascular Leakage in Healthy Volunteers.

Breaking Barriers: Characterization of the Intradermal Lipopolysaccharide Challenge as an In Vivo Model for Controlled Induction of Vascular Leakage in Healthy Volunteers.

Journal: Clinical pharmacology and therapeutics

Published: August 06, 2025

Navigating adverse immunostimulation: A practical guide for clinical researchers.

Navigating adverse immunostimulation: A practical guide for clinical researchers.

Journal: British journal of clinical pharmacology

Published: April 18, 2025

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience.

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience.

Journal: British journal of clinical pharmacology

Published: April 15, 2025

Showing 1-12 of 94

Last Updated: 09/26/2026