Mattia Freschi
Via Mario Negri 2
Milan, 20156, Italy
Milan, 20156, Italy
Last Updated: 09/26/2026
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Found 8 publications
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice.
Journal: Journal of neuroinflammation
Published: May 09, 2025
Novel P2X7 Antagonist Ameliorates the Early Phase of ALS Disease and Decreases Inflammation and Autophagy in SOD1-G93A Mouse Model.
Journal: International journal of molecular sciences
Published: August 31, 2021
A Novel HGF/SF Receptor (MET) Agonist Transiently Delays the Disease Progression in an Amyotrophic Lateral Sclerosis Mouse Model by Promoting Neuronal Survival and Dampening the Immune Dysregulation.
Journal: International journal of molecular sciences
Published: October 28, 2020
Multiple intracerebroventricular injections of human umbilical cord mesenchymal stem cells delay motor neurons loss but not disease progression of SOD1G93A mice.
Journal: Stem cell research
Published: March 31, 2017
Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience
Published: August 03, 2016
New Insights on the Mechanisms of Disease Course Variability in ALS from Mutant SOD1 Mouse Models.
Journal: Brain pathology (Zurich, Switzerland)
Published: January 08, 2016
ALS mouse model SOD1G93A displays early pathology of sensory small fibers associated to accumulation of a neurotoxic splice variant of peripherin.
Journal: Human molecular genetics
Published: November 28, 2015
Synthetic and natural small molecule TLR4 antagonists inhibit motoneuron death in cultures from ALS mouse model.
Journal: Pharmacological research
Published: September 03, 2015
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Last Updated: 09/26/2026