Maxie E. Kohler

R&d
Monheim Am Rhein, NW 40789, Germany

Last Updated: 09/26/2026

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Found 41 publications

Increased NFAT activity with dual CAR stimulation in CD19xCD22 CAR T-cells is associated with decreased exhaustion and improved survival.

Increased NFAT activity with dual CAR stimulation in CD19xCD22 CAR T-cells is associated with decreased exhaustion and improved survival.

Journal: Journal for immunotherapy of cancer
Published: October 29, 2025

Multiple Myeloma Cells Resistant to T-cell Therapies Exhibit a CD45+ Immunoevasive Phenotype.

Multiple Myeloma Cells Resistant to T-cell Therapies Exhibit a CD45+ Immunoevasive Phenotype.

Journal: Cancer immunology research
Published: August 27, 2025

International consensus guidelines for the conduct and reporting of CAR T-cell clinical trials in AML.

International consensus guidelines for the conduct and reporting of CAR T-cell clinical trials in AML.

Journal: Blood advances
Published: May 06, 2025

Rational redesign of antigen binding domain improves in vivo efficacy of the CD22-CAR.

Rational redesign of antigen binding domain improves in vivo efficacy of the CD22-CAR.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: April 08, 2025

T-bet overexpression enhances CAR T cell effector functions and antigen sensitivity.

T-bet overexpression enhances CAR T cell effector functions and antigen sensitivity.

Journal: Journal for immunotherapy of cancer
Published: April 07, 2025

Characterization of a multiplex digital PCR assay to quantify total T cells relative to chimeric antigen receptor-positive T cells.

Characterization of a multiplex digital PCR assay to quantify total T cells relative to chimeric antigen receptor-positive T cells.

Journal: Molecular therapy. Oncology
Published: September 24, 2024

Pesticide exposure of operators during mixing and loading a drone: towards a stratified exposure assessment.

Pesticide exposure of operators during mixing and loading a drone: towards a stratified exposure assessment.

Journal: Pest management science
Published: September 24, 2024

Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia.

Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia.

Journal: Cancer cell
Published: February 21, 2024

Antigen experience history directs distinct functional states of CD8+ CAR T cells during the anti-leukemia response.

Antigen experience history directs distinct functional states of CD8+ CAR T cells during the anti-leukemia response.

Journal: Research square
Published: January 10, 2024

Antigen experience history directs distinct functional states of CD8+ CAR T cells during the antileukemia response.

Antigen experience history directs distinct functional states of CD8+ CAR T cells during the antileukemia response.

Journal: Nature immunology
Published: December 05, 2023

Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8+ T cell adoptive therapies in pre-clinical studies.

Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8+ T cell adoptive therapies in pre-clinical studies.

Journal: Nature communications
Published: October 17, 2023

CD4+ CAR T cells - more than helpers.

CD4+ CAR T cells - more than helpers.

Journal: Nature cancer
Published: May 29, 2023
Showing 1-12 of 41

Last Updated: 09/26/2026