Maxinne Watchon

Level 1, 75 Talavera Road
Sydney, NSW 2109, Australia

Last Updated: 09/26/2026

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Found 18 publications

Investigating the pathogenic role of calpain proteases and the therapeutic potential of their inhibition in mice modelling Machado-Joseph disease.

Investigating the pathogenic role of calpain proteases and the therapeutic potential of their inhibition in mice modelling Machado-Joseph disease.

Journal: Human molecular genetics

Published: August 27, 2025

Gut transit and gut microbiome changes occur prior to the onset of motor impairment in a mouse model of Machado-Joseph disease.

Gut transit and gut microbiome changes occur prior to the onset of motor impairment in a mouse model of Machado-Joseph disease.

Journal: Neurobiology of disease

Published: June 10, 2025

Using fibre photometry with a fluorescence resonance energy transfer-based biosensor to test efficacy of calpain inhibitors in vivo.

Using fibre photometry with a fluorescence resonance energy transfer-based biosensor to test efficacy of calpain inhibitors in vivo.

Journal: Brain communications

Published: November 04, 2024

Spermidine treatment: induction of autophagy but also apoptosis?

Spermidine treatment: induction of autophagy but also apoptosis?

Journal: Molecular brain

Published: October 24, 2023

Autophagy Function and Benefits of Autophagy Induction in Models of Spinocerebellar Ataxia Type 3.

Autophagy Function and Benefits of Autophagy Induction in Models of Spinocerebellar Ataxia Type 3.

Journal: Cells

Published: December 15, 2022

Pathophysiological interplay between O-GlcNAc transferase and the Machado-Joseph disease protein ataxin-3.

Pathophysiological interplay between O-GlcNAc transferase and the Machado-Joseph disease protein ataxin-3.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: September 28, 2021

A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3.

A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3.

Journal: Cells

Published: July 09, 2021

Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.

Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.

Journal: Molecular brain

Published: May 03, 2021

Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3.

Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3.

Journal: Disease models & mechanisms

Published: March 18, 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Journal: Autophagy

Published: February 26, 2021

Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in CCNF Reveals Activation of the Apoptosis Pathway: A Workflow to Screen Pathogenic Gene Mutations.

Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in CCNF Reveals Activation of the Apoptosis Pathway: A Workflow to Screen Pathogenic Gene Mutations.

Journal: Frontiers in molecular neuroscience

Published: November 10, 2020

Conserved anti-inflammatory effects and sensing of butyrate in zebrafish.

Conserved anti-inflammatory effects and sensing of butyrate in zebrafish.

Journal: Gut microbes

Published: October 16, 2020

Showing 1-12 of 18

Last Updated: 09/26/2026