Megan Torvell

Maindy Road
Cardiff, WLS CF244HQ, United Kingdom

Last Updated: 09/26/2026

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Found 14 publications

The schizophrenia-associated gene CSMD1 encodes a complement classical pathway inhibitor predominantly expressed by astrocytes and at synapses in mice and humans.

The schizophrenia-associated gene CSMD1 encodes a complement classical pathway inhibitor predominantly expressed by astrocytes and at synapses in mice and humans.

Journal: Brain, behavior, and immunity

Published: November 08, 2024

Complement receptor 1 is expressed on brain cells and in the human brain.

Complement receptor 1 is expressed on brain cells and in the human brain.

Journal: Glia

Published: November 11, 2022

Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation.

Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation.

Journal: Brain pathology (Zurich, Switzerland)

Published: September 21, 2022

Terminal complement pathway activation drives synaptic loss in Alzheimer's disease models.

Terminal complement pathway activation drives synaptic loss in Alzheimer's disease models.

Journal: Acta neuropathologica communications

Published: May 06, 2022

Genetic Insights into the Impact of Complement in Alzheimer's Disease.

Genetic Insights into the Impact of Complement in Alzheimer's Disease.

Journal: Genes

Published: November 19, 2021

Exciting new tools for studying TREM2 in dementia.

Exciting new tools for studying TREM2 in dementia.

Journal: Structure (London, England : 1993)

Published: November 05, 2021

The Impact of Complement Genes on the Risk of Late-Onset Alzheimer's Disease.

The Impact of Complement Genes on the Risk of Late-Onset Alzheimer's Disease.

Journal: Genes

Published: February 27, 2021

Novel Monoclonal Antibodies Against Mouse C1q: Characterisation and Development of a Quantitative ELISA for Mouse C1q.

Novel Monoclonal Antibodies Against Mouse C1q: Characterisation and Development of a Quantitative ELISA for Mouse C1q.

Journal: Molecular neurobiology

Published: January 05, 2021

Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.

Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.

Journal: Nature communications

Published: July 24, 2020

HspB5 Activates a Neuroprotective Glial Cell Response in Experimental Tauopathy.

HspB5 Activates a Neuroprotective Glial Cell Response in Experimental Tauopathy.

Journal: Frontiers in neuroscience

Published: March 26, 2020

A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy.

A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy.

Journal: Alzheimer's & dementia (New York, N. Y.)

Published: October 26, 2019

Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System.

Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System.

Journal: Frontiers in immunology

Published: December 05, 2018

Showing 1-12 of 14

Last Updated: 09/26/2026