Mehlika D. Altıntop

Eskisehir, 26470, Turkey

Last Updated: 09/26/2026

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Found 57 publications

Development of thiazole-hydrazone hybrids for targeted therapy of non-small cell lung cancer.

Development of thiazole-hydrazone hybrids for targeted therapy of non-small cell lung cancer.

Journal: Bioorganic chemistry

Published: April 27, 2026

Development of a new series of thiazoles as EGFR-targeted anticancer agents for NSCLC therapy through nanotechnological and computer-aided approaches.

Development of a new series of thiazoles as EGFR-targeted anticancer agents for NSCLC therapy through nanotechnological and computer-aided approaches.

Journal: Bioorganic chemistry

Published: December 06, 2025

Design, synthesis, in vitro and in silico evaluation of thiazole-hydrazone hybrids as potent and safe α-glucosidase inhibitors.

Design, synthesis, in vitro and in silico evaluation of thiazole-hydrazone hybrids as potent and safe α-glucosidase inhibitors.

Journal: Bioorganic chemistry

Published: July 29, 2025

Design, synthesis and biological evaluation of a new series of imidazothiazole-hydrazone hybrids as dual EGFR and Akt inhibitors for NSCLC therapy.

Design, synthesis and biological evaluation of a new series of imidazothiazole-hydrazone hybrids as dual EGFR and Akt inhibitors for NSCLC therapy.

Journal: European journal of medicinal chemistry

Published: April 16, 2024

Discovery of Small Molecule COX-1 and Akt Inhibitors as Anti-NSCLC Agents Endowed with Anti-Inflammatory Action.

Discovery of Small Molecule COX-1 and Akt Inhibitors as Anti-NSCLC Agents Endowed with Anti-Inflammatory Action.

Journal: International journal of molecular sciences

Published: December 05, 2022

A new series of hydrazones as small-molecule aldose reductase inhibitors.

A new series of hydrazones as small-molecule aldose reductase inhibitors.

Journal: Archiv der Pharmazie

Published: November 03, 2022

A new series of thiazole-hydrazone hybrids for Akt-targeted therapy of non-small cell lung cancer.

A new series of thiazole-hydrazone hybrids for Akt-targeted therapy of non-small cell lung cancer.

Journal: Drug development research

Published: October 12, 2022

Design, synthesis and biological evaluation of a new series of arylidene indanones as small molecules for targeted therapy of non-small cell lung carcinoma and prostate cancer.

Design, synthesis and biological evaluation of a new series of arylidene indanones as small molecules for targeted therapy of non-small cell lung carcinoma and prostate cancer.

Journal: European journal of medicinal chemistry

Published: September 06, 2022

A new series of thiosemicarbazone-based anti-inflammatory agents exerting their action through cyclooxygenase inhibition.

A new series of thiosemicarbazone-based anti-inflammatory agents exerting their action through cyclooxygenase inhibition.

Journal: Archiv der Pharmazie

Published: March 17, 2022

A New Series of Indeno[1,2-c]pyrazoles as EGFR TK Inhibitors for NSCLC Therapy.

A New Series of Indeno[1,2-c]pyrazoles as EGFR TK Inhibitors for NSCLC Therapy.

Journal: Molecules (Basel, Switzerland)

Published: December 06, 2021

EGFR-Targeted Pentacyclic Triterpene Analogues for Glioma Therapy.

EGFR-Targeted Pentacyclic Triterpene Analogues for Glioma Therapy.

Journal: International journal of molecular sciences

Published: August 26, 2021

Novel metabolic enzyme inhibitors designed through the molecular hybridization of thiazole and pyrazoline scaffolds.

Novel metabolic enzyme inhibitors designed through the molecular hybridization of thiazole and pyrazoline scaffolds.

Journal: Archiv der Pharmazie

Published: August 09, 2021

Showing 1-12 of 57

Last Updated: 09/26/2026