Melek Simsek

Amsterdam, NH, Netherlands

Last Updated: 09/26/2026

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Found 29 publications

Early Crohn's disease: can we change the disease course?

Early Crohn's disease: can we change the disease course?

Journal: Nature reviews. Gastroenterology & hepatology

Published: May 14, 2025

Early therapeutic drug monitoring helps to identify inflammatory bowel disease patients with a high risk to fail thiopurine treatment.

Early therapeutic drug monitoring helps to identify inflammatory bowel disease patients with a high risk to fail thiopurine treatment.

Journal: British journal of clinical pharmacology

Published: March 29, 2024

Multicentre study and systematic review: Allopurinol exposure during pregnancy.

Multicentre study and systematic review: Allopurinol exposure during pregnancy.

Journal: Alimentary pharmacology & therapeutics

Published: January 11, 2024

Drug rediscovery in gastroenterology: from off-label to on-label use of thioguanine in inflammatory bowel disease.

Drug rediscovery in gastroenterology: from off-label to on-label use of thioguanine in inflammatory bowel disease.

Journal: Gut

Published: February 09, 2023

Thioguanine is Effective as Maintenance Therapy for Inflammatory Bowel Disease: A Prospective Multicentre Registry Study.

Thioguanine is Effective as Maintenance Therapy for Inflammatory Bowel Disease: A Prospective Multicentre Registry Study.

Journal: Journal of Crohn's & colitis

Published: January 26, 2023

Exposure to Thioguanine During 117 Pregnancies in Women With Inflammatory Bowel Disease.

Exposure to Thioguanine During 117 Pregnancies in Women With Inflammatory Bowel Disease.

Journal: Journal of Crohn's & colitis

Published: December 15, 2022

Predictive Algorithm for Thiopurine-Induced Hepatotoxicity in Inflammatory Bowel Disease Patients.

Predictive Algorithm for Thiopurine-Induced Hepatotoxicity in Inflammatory Bowel Disease Patients.

Journal: Therapeutic drug monitoring

Published: June 03, 2022

Rectally Administrated Thioguanine for Distal Ulcerative Colitis: A Multicenter Case Series.

Rectally Administrated Thioguanine for Distal Ulcerative Colitis: A Multicenter Case Series.

Journal: Inflammatory bowel diseases

Published: April 28, 2022

Correction to: Efficacy, safety and drug survival of thioguanine as maintenance treatment for inflammatory bowel disease: a retrospective multi-centre study in the United Kingdom.

Correction to: Efficacy, safety and drug survival of thioguanine as maintenance treatment for inflammatory bowel disease: a retrospective multi-centre study in the United Kingdom.

Journal: BMC gastroenterology

Published: April 27, 2022

Thioguanine Therapy in Inflammatory Bowel Diseases. A Practical Guide.

Thioguanine Therapy in Inflammatory Bowel Diseases. A Practical Guide.

Journal: Journal of gastrointestinal and liver diseases : JGLD

Published: June 30, 2020

Letter: off-label use of hyperbaric oxygen therapy in inflammatory bowel disease-Authors' reply.

Letter: off-label use of hyperbaric oxygen therapy in inflammatory bowel disease-Authors' reply.

Journal: Alimentary pharmacology & therapeutics

Published: June 13, 2020

Efficacy, safety and drug survival of thioguanine as maintenance treatment for inflammatory bowel disease: a retrospective multi-centre study in the United Kingdom.

Efficacy, safety and drug survival of thioguanine as maintenance treatment for inflammatory bowel disease: a retrospective multi-centre study in the United Kingdom.

Journal: BMC gastroenterology

Published: March 06, 2020

Showing 1-12 of 29

Last Updated: 09/26/2026