Mengbi Guo

Key Laboratory Of Structure Based Drugs Design And Discovery
Shenyang, 110016, China

Last Updated: 09/26/2026

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Found 8 publications

Discovery of Subnanomolar and Highly Selective Carbonic Anhydrase II Inhibitors Featuring L-Shaped Scaffolds via Active-Site-Matched Fragment Growing.

Discovery of Subnanomolar and Highly Selective Carbonic Anhydrase II Inhibitors Featuring L-Shaped Scaffolds via Active-Site-Matched Fragment Growing.

Journal: Journal of medicinal chemistry

Published: June 15, 2026

Discovery of anti-glaucoma agents with dual hCA II inhibitory and nitric oxide-releasing activity and their neuroprotective effects.

Discovery of anti-glaucoma agents with dual hCA II inhibitory and nitric oxide-releasing activity and their neuroprotective effects.

Journal: European journal of medicinal chemistry

Published: February 13, 2026

Discovery of Novel NO-Donor Containing hCA II Inhibitors with Retinal Ganglion Cell-Protective Effects for the Efficient Treatment of Glaucoma.

Discovery of Novel NO-Donor Containing hCA II Inhibitors with Retinal Ganglion Cell-Protective Effects for the Efficient Treatment of Glaucoma.

Journal: Journal of medicinal chemistry

Published: December 18, 2025

Discovery of Novel α,β-Unsaturated Amide Derivatives as Candidate Antifungals to Overcome Fungal Resistance.

Discovery of Novel α,β-Unsaturated Amide Derivatives as Candidate Antifungals to Overcome Fungal Resistance.

Journal: Journal of medicinal chemistry

Published: July 30, 2024

Developing Novel Coumarin-Containing Azoles Antifungal Agents by the Scaffold Merging Strategy for Treating Azole-Resistant Candidiasis.

Developing Novel Coumarin-Containing Azoles Antifungal Agents by the Scaffold Merging Strategy for Treating Azole-Resistant Candidiasis.

Journal: Journal of medicinal chemistry

Published: September 19, 2023

Discovery of novel artemisinin-sulfonamidehybrids as potential carbonicanhydraseIX inhibitors with improved antiproliferative activities.

Discovery of novel artemisinin-sulfonamidehybrids as potential carbonicanhydraseIX inhibitors with improved antiproliferative activities.

Journal: Bioorganic chemistry

Published: August 11, 2020

Design, synthesis and biological evaluation of novel carbohydrate-based sulfonamide derivatives as antitumor agents.

Design, synthesis and biological evaluation of novel carbohydrate-based sulfonamide derivatives as antitumor agents.

Journal: Bioorganic chemistry

Published: June 24, 2020

Design, Synthesis and Antifungal Activity of Novel Benzofuran-Triazole Hybrids.

Design, Synthesis and Antifungal Activity of Novel Benzofuran-Triazole Hybrids.

Journal: Molecules (Basel, Switzerland)

Published: April 20, 2016

Showing 1-8 of 8

Last Updated: 09/26/2026