Mengnan Xu
Halifax, NS, Canada
Last Updated: 09/26/2026
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Found 12 publications
Endosome-ER contact sites in phagophore formation.
Journal: Trends in cell biology
Published: July 01, 2025
Targeting TRPML3 inhibits proliferation and invasion, and enhances doxorubicin sensitivity by disrupting lysosomal acidification and mitochondrial function in triple-negative breast cancer.
Journal: Biochimica et biophysica acta. Molecular cell research
Published: September 17, 2024
MCOLN/TRPML channels in the regulation of MTORC1 and autophagy.
Journal: Autophagy
Published: January 05, 2024
TRPML3/BK complex promotes autophagy and bacterial clearance by providing a positive feedback regulation of mTOR via PI3P.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 16, 2023
Lysosomal ATP Transporter SLC17A9 Controls Cell Viability via Regulating Cathepsin D.
Journal: Cells
Published: August 28, 2021
A lysosomal K+ channel regulates large particle phagocytosis by facilitating lysosome Ca2+ release.
Journal: Scientific reports
Published: July 24, 2019
The lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways.
Journal: Cell calcium
Published: February 21, 2019
Lysosomal Ca2+ release channel TRPML1 regulates lysosome size by promoting mTORC1 activity.
Journal: European journal of cell biology
Published: May 22, 2018
Showing 1-12 of 12
Last Updated: 09/26/2026