Mette G. Jensen
Aarhus C, Denmark
Last Updated: 09/26/2026
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Found 9 publications
A luminescent reporter assay to quantify SORL1 ectodomain shedding and retromer-dependent endosome recycling activity.
Journal: The Journal of biological chemistry
Published: October 02, 2025
Soluble SORL1 in cerebrospinal fluid as a marker for functional impact of rare SORL1 variants.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: September 12, 2025
Domain mapping of disease mutations reveals pathogenic SORL1 variants in Alzheimer's disease.
Journal: Molecular neurodegeneration
Published: February 20, 2025
The SORL1 p.Y1816C variant causes impaired endosomal dimerization and autosomal dominant Alzheimer's disease.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: September 03, 2024
SorLA restricts TNFα release from microglia to shape a glioma-supportive brain microenvironment.
Journal: EMBO reports
Published: August 30, 2023
Epitope mapping of nanobodies binding the Alzheimer's disease receptor SORLA.
Journal: Journal of biotechnology
Published: May 09, 2023
Dimerization of the Alzheimer's disease pathogenic receptor SORLA regulates its association with retromer.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 18, 2023
A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.
Journal: Cell reports. Medicine
Published: August 16, 2021
Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer's disease.
Journal: Acta neuropathologica communications
Published: February 22, 2021
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Last Updated: 09/26/2026