Michael A. Geeves

Canterbury, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 82 publications

The E525K β-Myosin Mutation Causes Hypocontractility in Cardiomyocytes Without Altering Loaded Crossbridge Cycling.

The E525K β-Myosin Mutation Causes Hypocontractility in Cardiomyocytes Without Altering Loaded Crossbridge Cycling.

Journal: bioRxiv : the preprint server for biology

Published: July 03, 2026

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model.

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model.

Journal: bioRxiv : the preprint server for biology

Published: September 15, 2025

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model.

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model.

Journal: Journal of molecular and cellular cardiology

Published: August 21, 2025

Direct measurement of mavacamten and deoxyATP perturbation of the SRX/DRX ratio in porcine cardiac myofibrils using a simple, accessible and multiplexed approach.

Direct measurement of mavacamten and deoxyATP perturbation of the SRX/DRX ratio in porcine cardiac myofibrils using a simple, accessible and multiplexed approach.

Journal: Journal of muscle research and cell motility

Published: July 25, 2025

Extracellular vesicle-linked vitamin B12 acquisition via novel binding proteins in Bacteroides thetaiotaomicron.

Extracellular vesicle-linked vitamin B12 acquisition via novel binding proteins in Bacteroides thetaiotaomicron.

Journal: The Biochemical journal

Published: July 23, 2025

Rapid changes in hydrostatic pressure as a probe for correlating function of purified proteins with their measured activity in living cells.

Rapid changes in hydrostatic pressure as a probe for correlating function of purified proteins with their measured activity in living cells.

Journal: Biophysical reviews

Published: April 22, 2025

Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and Worms.

Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and Worms.

Journal: Cytoskeleton (Hoboken, N.J.)

Published: February 20, 2025

Interacting myosin head dynamics and their modification by 2'-deoxy-ADP.

Interacting myosin head dynamics and their modification by 2'-deoxy-ADP.

Journal: Biophysical journal

Published: August 01, 2024

Spatially resolving how cMyBP-C phosphorylation and haploinsufficiency in porcine and human myofibrils affect β-cardiac myosin activity.

Spatially resolving how cMyBP-C phosphorylation and haploinsufficiency in porcine and human myofibrils affect β-cardiac myosin activity.

Journal: The Journal of general physiology

Published: June 29, 2024

An atomistic model of myosin interacting heads motif dynamics and their modification by 2'-deoxy-ADP.

An atomistic model of myosin interacting heads motif dynamics and their modification by 2'-deoxy-ADP.

Journal: bioRxiv : the preprint server for biology

Published: June 19, 2024

Myosin's powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin.

Myosin's powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin.

Journal: The Journal of general physiology

Published: January 02, 2024

Motor domain phosphorylation increases nucleotide exchange and turns MYO6 into a faster and stronger motor.

Motor domain phosphorylation increases nucleotide exchange and turns MYO6 into a faster and stronger motor.

Journal: Nature communications

Published: December 21, 2023

Showing 1-12 of 82

Last Updated: 09/26/2026