Last Updated: 09/26/2026
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Found 93 publications
Cryo-EM structure and biochemical characterization of a BRAF/CRAF heterodimer: Negative charge in the NtA motif is not required for RAF activation.
Journal: bioRxiv : the preprint server for biology
Published: May 25, 2026
Editorial Expression of Concern: Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia.
Journal: Leukemia
Published: May 06, 2026
Overcoming EGFR resistance by monovalent and bident inhibitors targeting Cys775.
Journal: bioRxiv : the preprint server for biology
Published: January 23, 2026
RAF isoform selectivity of MEK inhibitors and rational design of a covalent ARAF-MEK inhibitor.
Journal: bioRxiv : the preprint server for biology
Published: December 25, 2025
Recurrent Resistance Mutations to Lirafugratinib Inform Treatment Sequencing in FGFR2-Driven Tumors.
Recurrent Resistance Mutations to Lirafugratinib Inform Treatment Sequencing in FGFR2-Driven Tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: November 15, 2025
Author Correction: A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas.
Journal: Nature communications
Published: October 09, 2025
Characterization and inhibitor sensitivity of ARAF, BRAF, and CRAF complexes.
Journal: bioRxiv : the preprint server for biology
Published: August 20, 2025
Allosteric inhibition of JAK2 with lysine-reactive compounds that bind the pseudokinase domain.
Journal: European journal of medicinal chemistry
Published: August 08, 2025
Characterization and inhibitor sensitivity of ARAF, BRAF, and CRAF kinases.
Journal: The Journal of biological chemistry
Published: July 30, 2025
ErbB family receptor dimerization dynamics and dysregulation via long-term single-molecule imaging.
Journal: Cell
Published: June 23, 2025
Cryo-EM structures of CRAF/MEK1/14-3-3 complexes in autoinhibited and open-monomer states reveal features of RAF regulation.
Journal: Nature communications
Published: June 11, 2025
Last Updated: 09/26/2026