Michael J. Knapp

Michael J. Knapp

Family Medicine
105 S State St
Suite 113
Aberdeen, SD 57401

Last Updated: 09/26/2026

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Found 19 publications

Dynamic Domain Links Substrate Binding and Catalysis in the Factor-Inhibiting-HIF-1.

Dynamic Domain Links Substrate Binding and Catalysis in the Factor-Inhibiting-HIF-1.

Journal: Biochemistry
Published: August 01, 2023

Measurement of kinetic isotope effects on peptide hydroxylation using MALDI-MS.

Measurement of kinetic isotope effects on peptide hydroxylation using MALDI-MS.

Journal: Methods in enzymology
Published: January 22, 2023

Kinetic Studies of the Hydrogen Atom Transfer in a Hypoxia-Sensing Enzyme, FIH-1: KIE and O2 Reactivity.

Kinetic Studies of the Hydrogen Atom Transfer in a Hypoxia-Sensing Enzyme, FIH-1: KIE and O2 Reactivity.

Journal: Biochemistry
Published: October 29, 2021

Protein Flexibility of the α-Ketoglutarate-Dependent Oxygenase Factor-Inhibiting HIF-1: Implications for Substrate Binding, Catalysis, and Regulation.

Protein Flexibility of the α-Ketoglutarate-Dependent Oxygenase Factor-Inhibiting HIF-1: Implications for Substrate Binding, Catalysis, and Regulation.

Journal: Biochemistry
Published: September 10, 2019

Antioxidant capacity and anoxia tolerance in Austrofundulus limnaeus embryos.

Antioxidant capacity and anoxia tolerance in Austrofundulus limnaeus embryos.

Journal: The Journal of experimental biology
Published: April 01, 2019

Chloride Supports O2 Activation in the D201G Facial Triad Variant of Factor-Inhibiting Hypoxia Inducible Factor, an α-Ketoglutarate Dependent Oxygenase.

Chloride Supports O2 Activation in the D201G Facial Triad Variant of Factor-Inhibiting Hypoxia Inducible Factor, an α-Ketoglutarate Dependent Oxygenase.

Journal: Inorganic chemistry
Published: September 26, 2018

Investigations on the role of a solvent tunnel in the α-ketoglutarate dependent oxygenase factor inhibiting HIF (FIH).

Investigations on the role of a solvent tunnel in the α-ketoglutarate dependent oxygenase factor inhibiting HIF (FIH).

Journal: Journal of inorganic biochemistry
Published: September 30, 2016

The facial triad in the α-ketoglutarate dependent oxygenase FIH: A role for sterics in linking substrate binding to O2 activation.

The facial triad in the α-ketoglutarate dependent oxygenase FIH: A role for sterics in linking substrate binding to O2 activation.

Journal: Journal of inorganic biochemistry
Published: July 26, 2016

Substrate Promotes Productive Gas Binding in the α-Ketoglutarate-Dependent Oxygenase FIH.

Substrate Promotes Productive Gas Binding in the α-Ketoglutarate-Dependent Oxygenase FIH.

Journal: Biochemistry
Published: January 06, 2016

Increased Turnover at Limiting O2 Concentrations by the Thr(387) → Ala Variant of HIF-Prolyl Hydroxylase PHD2.

Increased Turnover at Limiting O2 Concentrations by the Thr(387) → Ala Variant of HIF-Prolyl Hydroxylase PHD2.

Journal: Biochemistry
Published: April 11, 2015

The rate-limiting step of O2 activation in the α-ketoglutarate oxygenase factor inhibiting hypoxia inducible factor.

The rate-limiting step of O2 activation in the α-ketoglutarate oxygenase factor inhibiting hypoxia inducible factor.

Journal: Biochemistry
Published: November 26, 2014

Substrate positioning by Gln(239) stimulates turnover in factor inhibiting HIF, an αKG-dependent hydroxylase.

Substrate positioning by Gln(239) stimulates turnover in factor inhibiting HIF, an αKG-dependent hydroxylase.

Journal: Biochemistry
Published: August 15, 2014
Showing 1-12 of 19

Last Updated: 09/26/2026