Michael O. Hottiger

Zurich, ZH, Switzerland

Last Updated: 09/26/2026

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Found 99 publications

From Bench to Clinic: The 2024 FASEB Scientific Research Conference on NAD Metabolism and Signaling.

From Bench to Clinic: The 2024 FASEB Scientific Research Conference on NAD Metabolism and Signaling.

Journal: Molecular medicine (Cambridge, Mass.)

Published: August 28, 2025

PARP1 inhibition in naïve mouse embryonic stem cells induces viral mimicry.

PARP1 inhibition in naïve mouse embryonic stem cells induces viral mimicry.

Journal: Nucleic acids research

Published: July 24, 2025

Expanding the Perspective on PARP1 and Its Inhibitors in Cancer Therapy: From DNA Damage Repair to Immunomodulation.

Expanding the Perspective on PARP1 and Its Inhibitors in Cancer Therapy: From DNA Damage Repair to Immunomodulation.

Journal: Biomedicines

Published: June 18, 2024

Unleashing viral mimicry: A combinatorial strategy to enhance the efficacy of PARP7 inhibitors.

Unleashing viral mimicry: A combinatorial strategy to enhance the efficacy of PARP7 inhibitors.

Journal: BioEssays : news and reviews in molecular, cellular and developmental biology

Published: April 11, 2024

DNA Methyltransferase Inhibition Upregulates the Costimulatory Molecule ICAM-1 and the Immunogenic Phenotype of Melanoma Cells.

DNA Methyltransferase Inhibition Upregulates the Costimulatory Molecule ICAM-1 and the Immunogenic Phenotype of Melanoma Cells.

Journal: JID innovations : skin science from molecules to population health

Published: January 26, 2024

PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis.

PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 27, 2023

PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency.

PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency.

Journal: EMBO reports

Published: September 13, 2023

Poly(ADP-Ribose) Polymerase-1 Lacking Enzymatic Activity Is Not Compatible with Mouse Development.

Poly(ADP-Ribose) Polymerase-1 Lacking Enzymatic Activity Is Not Compatible with Mouse Development.

Journal: Cells

Published: June 24, 2023

Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex.

Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex.

Journal: Cell reports

Published: April 20, 2023

Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma.

Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma.

Journal: Cancer research

Published: February 14, 2023

Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels.

Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels.

Journal: Nucleic acids research

Published: January 13, 2023

Subcellular Quantitation of ADP-Ribosylation by High-Content Microscopy.

Subcellular Quantitation of ADP-Ribosylation by High-Content Microscopy.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: December 14, 2022

Showing 1-12 of 99

Last Updated: 09/26/2026