Michael R. Hughes

Vancouver, BC, Canada

Last Updated: 09/26/2026

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Found 51 publications

Early-life microbiota skews long-term gene expression and chromatin states of bone marrow hematopoietic precursors.

Early-life microbiota skews long-term gene expression and chromatin states of bone marrow hematopoietic precursors.

Journal: Cell reports
Published: May 18, 2025

Microbial dysbiosis sculpts a systemic ILC3/IL-17 axis governing lung inflammatory responses and central hematopoiesis.

Microbial dysbiosis sculpts a systemic ILC3/IL-17 axis governing lung inflammatory responses and central hematopoiesis.

Journal: Mucosal immunology
Published: March 17, 2025

Functional targeting of ILC2s and ILC3s reveals selective roles in intestinal fibrosis and homeostasis.

Functional targeting of ILC2s and ILC3s reveals selective roles in intestinal fibrosis and homeostasis.

Journal: The Journal of experimental medicine
Published: September 10, 2024

Type-2 innate signals are dispensable for skeletal muscle regeneration and pathology linked to Duchenne muscular dystrophy.

Type-2 innate signals are dispensable for skeletal muscle regeneration and pathology linked to Duchenne muscular dystrophy.

Journal: EMBO reports
Published: April 28, 2024

Microbial intestinal dysbiosis drives long-term allergic susceptibility by sculpting an ILC2-B1 cell-innate IgE axis.

Microbial intestinal dysbiosis drives long-term allergic susceptibility by sculpting an ILC2-B1 cell-innate IgE axis.

Journal: The Journal of allergy and clinical immunology
Published: February 27, 2024

A tumor-restricted glycoform of podocalyxin is a highly selective marker of immunologically cold high-grade serous ovarian carcinoma.

A tumor-restricted glycoform of podocalyxin is a highly selective marker of immunologically cold high-grade serous ovarian carcinoma.

Journal: Frontiers in oncology
Published: August 31, 2023

Prognostic peripheral blood biomarkers at ICU admission predict COVID-19 clinical outcomes.

Prognostic peripheral blood biomarkers at ICU admission predict COVID-19 clinical outcomes.

Journal: Frontiers in immunology
Published: August 02, 2022

Antibody-Drug Conjugates Targeting Tumor-Specific Mucin Glycoepitopes.

Antibody-Drug Conjugates Targeting Tumor-Specific Mucin Glycoepitopes.

Journal: Frontiers in bioscience (Landmark edition)
Published: July 16, 2022

Platelet signaling at the nexus of innate immunity and rheumatoid arthritis.

Platelet signaling at the nexus of innate immunity and rheumatoid arthritis.

Journal: Frontiers in immunology
Published: June 24, 2022

"Just one word, plastic!": Controversies and caveats in innate lymphoid cell plasticity.

"Just one word, plastic!": Controversies and caveats in innate lymphoid cell plasticity.

Journal: Frontiers in immunology
Published: May 18, 2022

Platelet factor 4 (CXCL4/PF4) upregulates matrix metalloproteinase-2 (MMP-2) in gingival fibroblasts.

Platelet factor 4 (CXCL4/PF4) upregulates matrix metalloproteinase-2 (MMP-2) in gingival fibroblasts.

Journal: Scientific reports
Published: May 17, 2022

Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models.

Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models.

Journal: Frontiers in oncology
Published: January 17, 2022
Showing 1-12 of 51

Last Updated: 09/26/2026