Michael Ruhl
Frankfurt Am Main, HE, Germany
Last Updated: 09/26/2026
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Found 21 publications
Analysis of Oligonucleotide Stability and Fragmentation: Impact of 2'-Modifications, Base Composition, and Charge-States.
Journal: Rapid communications in mass spectrometry : RCM
Published: December 18, 2025
Considerations for deconvolution of oligonucleotide mass spectra in quality control.
Journal: Analytical methods : advancing methods and applications
Published: September 22, 2025
Impact of nucleotide hydrophobicity on oligonucleotides separation in liquid chromatography.
Journal: Journal of chromatography. A
Published: March 10, 2025
Full sequencing of 100mer sgRNA via tandem mass spectrometry by targeted RNase H digestion with customized probes.
Journal: Analytical and bioanalytical chemistry
Published: October 25, 2024
Sequence confirmation of synthetic DNA exceeding 100 nucleotides using restriction enzyme mediated digestion combined with high-resolution tandem mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis
Published: December 21, 2023
Quantification of Oligonucleotides Using Tandem Mass Spectrometry with Isobaric Internal Standards.
Journal: International journal of molecular sciences
Published: August 28, 2023
Identifying Patients with Polycythemia Vera at Risk of Thrombosis after Hydroxyurea Initiation: The Polycythemia Vera-Advanced Integrated Models (PV-AIM) Project.
Journal: Biomedicines
Published: May 09, 2023
Investigation of the Influence of Charge State and Collision Energy on Oligonucleotide Fragmentation by Tandem Mass Spectrometry.
Journal: Molecules (Basel, Switzerland)
Published: December 15, 2022
Precision reimbursement for precision medicine: the need for patient-level decisions between payers, providers and pharmaceutical companies.
Journal: Future healthcare journal
Published: December 10, 2021
Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms.
Journal: International journal of molecular sciences
Published: October 29, 2020
Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis.
Journal: Nature chemistry
Published: November 27, 2019
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 01, 2018
Last Updated: 09/26/2026