Last Updated: 09/26/2026
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Found 6 publications
Identification and Optimization of Benzimidazole Sulfonamides as Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists with in Vivo Activity.
Journal: Journal of medicinal chemistry
Published: August 21, 2015
Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy.
Journal: Antimicrobial agents and chemotherapy
Published: April 07, 2015
Discovery of heterocyclic sulfonamides as sphingosine 1-phosphate receptor 1 (S1P1) antagonists.
Journal: Bioorganic & medicinal chemistry letters
Published: March 12, 2015
Pyridodiazepine amines are selective therapeutic agents for helicobacter pylori by suppressing growth through inhibition of glutamate racemase but are predicted to require continuous elevated levels in plasma to achieve clinical efficacy.
Journal: Antimicrobial agents and chemotherapy
Published: February 04, 2015
Discovery of a novel class of dimeric Smac mimetics as potent IAP antagonists resulting in a clinical candidate for the treatment of cancer (AZD5582).
Journal: Journal of medicinal chemistry
Published: December 11, 2013
Discovery of bacterial NAD⁺-dependent DNA ligase inhibitors: improvements in clearance of adenosine series.
Journal: Bioorganic & medicinal chemistry letters
Published: October 12, 2011
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Last Updated: 09/26/2026