Michael Themis

UCL Great Ormond Street Institute Of Child Health
London, ENG WC1N1EH, United Kingdom

Last Updated: 09/26/2026

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Found 16 publications

Transcriptomic Profiling of iPS Cell-Derived Hepatocyte-like Cells Reveals Their Close Similarity to Primary Liver Hepatocytes.

Transcriptomic Profiling of iPS Cell-Derived Hepatocyte-like Cells Reveals Their Close Similarity to Primary Liver Hepatocytes.

Journal: Cells
Published: May 20, 2025

Analysis of HIV-1-Based Lentiviral Vector Particle Composition by PacBio Long-Read Nucleic Acid Sequencing.

Analysis of HIV-1-Based Lentiviral Vector Particle Composition by PacBio Long-Read Nucleic Acid Sequencing.

Journal: Human gene therapy
Published: February 20, 2025

Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article.

Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article.

Journal: Human gene therapy
Published: July 25, 2024

hInGeTox: a human-based in vitro platform to evaluate lentivirus/host interactions that contribute to genotoxicity.

hInGeTox: a human-based in vitro platform to evaluate lentivirus/host interactions that contribute to genotoxicity.

Journal: Gene therapy
Published: January 05, 2024

Optimised protocols to generate high titre lentiviral vectors using a novel transfection agent enabling extended HEK293T culture following transient transfection and suspension culture.

Optimised protocols to generate high titre lentiviral vectors using a novel transfection agent enabling extended HEK293T culture following transient transfection and suspension culture.

Journal: Journal of virological methods
Published: June 06, 2023

HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival.

HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival.

Journal: Gene therapy
Published: April 07, 2021

Rapid and inexpensive purification of adenovirus vectors using an optimised aqueous two-phase technology.

Rapid and inexpensive purification of adenovirus vectors using an optimised aqueous two-phase technology.

Journal: Journal of virological methods
Published: October 27, 2020

Serum Free Production of Three-dimensional Human Hepatospheres from Pluripotent Stem Cells.

Serum Free Production of Three-dimensional Human Hepatospheres from Pluripotent Stem Cells.

Journal: Journal of visualized experiments : JoVE
Published: August 06, 2019

Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia.

Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia.

Journal: Non-coding RNA research
Published: September 26, 2018

Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus Envelopes.

Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus Envelopes.

Journal: Molecular therapy. Methods & clinical development
Published: March 23, 2018

Three-dimensional cell culture: from evolution to revolution.

Three-dimensional cell culture: from evolution to revolution.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Published: March 19, 2018

Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblasts.

Lentivirus-meditated frataxin gene delivery reverses genome instability in Friedreich ataxia patient and mouse model fibroblasts.

Journal: Gene therapy
Published: October 14, 2015
Showing 1-12 of 16

Last Updated: 09/26/2026