Last Updated: 09/26/2026
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Found 11 publications
Therapeutic Drug Distribution across the Mouse Brain Is Heterogeneous as Revealed by In Vivo, Spatially Resolved Aptamer-Based Sensing.
Journal: ACS pharmacology & translational science
Published: October 01, 2024
Identification and Characterization of a Blood-Brain Barrier Penetrant Inositol Hexakisphosphate Kinase (IP6K) Inhibitor.
Journal: Journal of medicinal chemistry
Published: August 03, 2024
The IP6K Inhibitor LI-2242 Ameliorates Diet-Induced Obesity, Hyperglycemia, and Hepatic Steatosis in Mice by Improving Cell Metabolism and Insulin Signaling.
Journal: Biomolecules
Published: April 03, 2023
Identification of Small-Molecule Inhibitors of Human Inositol Hexakisphosphate Kinases by High-Throughput Screening.
Journal: ACS pharmacology & translational science
Published: December 20, 2020
Inhibition of Human Uracil DNA Glycosylase Sensitizes a Large Fraction of Colorectal Cancer Cells to 5-Fluorodeoxyuridine and Raltitrexed but Not Fluorouracil.
Journal: Molecular pharmacology
Published: October 27, 2020
Membrane bound catechol-O-methytransferase is the dominant isoform for dopamine metabolism in PC12 cells and rat brain.
Journal: European journal of pharmacology
Published: September 12, 2020
Development of a PC12 Cell Based Assay for Screening Catechol-O-methyltransferase Inhibitors.
Journal: ACS chemical neuroscience
Published: September 07, 2019
Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol O-Methyltransferase.
Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol O-Methyltransferase.
Journal: ACS medicinal chemistry letters
Published: September 06, 2019
Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility.
Journal: Psychopharmacology
Published: March 13, 2019
Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol O-Methyltransferase.
Journal: Journal of medicinal chemistry
Published: October 02, 2018
Design, synthesis, and structure-activity relationships of pyridoquinazolinecarboxamides as RNA polymerase I inhibitors.
Journal: Journal of medicinal chemistry
Published: May 23, 2014
Showing 1-11 of 11
Last Updated: 09/26/2026