Michal Hocek

Prague, PR 16000, Czech Republic

Last Updated: 09/26/2026

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Found 132 publications

Reactive DNA Probes for Cross-Linking with Specific Amino Acids of Protein.

Reactive DNA Probes for Cross-Linking with Specific Amino Acids of Protein.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: August 01, 2026

Biotin- and Chloroalkane-Modified Nucleotides for Dual Display of Proteins on DNA Through Streptavidin and Halotag Binding.

Biotin- and Chloroalkane-Modified Nucleotides for Dual Display of Proteins on DNA Through Streptavidin and Halotag Binding.

Journal: Angewandte Chemie (International ed. in English)

Published: April 28, 2026

Synthesis and Biological Activity of 2,6-Disubstituted and 2,6,9-Trisubstituted 7-Deazapurine Nucleobases.

Synthesis and Biological Activity of 2,6-Disubstituted and 2,6,9-Trisubstituted 7-Deazapurine Nucleobases.

Journal: ChemMedChem

Published: December 19, 2025

Enzymatic Synthesis of Modified RNA Containing 5-Methyl- or 5-Ethylpyrimidines or Substituted 7-Deazapurines and Influence of the Modifications on Stability, Translation, and CRISPR-Cas9 Cleavage.

Enzymatic Synthesis of Modified RNA Containing 5-Methyl- or 5-Ethylpyrimidines or Substituted 7-Deazapurines and Influence of the Modifications on Stability, Translation, and CRISPR-Cas9 Cleavage.

Journal: ACS chemical biology

Published: November 06, 2025

Potent Competitive Inhibitors of Ecto-5'-nucleotidase (CD73) based on 6‑(Het)aryl-7-deazapurine Ribonucleoside 5'‑O‑Bisphosphonates.

Potent Competitive Inhibitors of Ecto-5'-nucleotidase (CD73) based on 6‑(Het)aryl-7-deazapurine Ribonucleoside 5'‑O‑Bisphosphonates.

Journal: ACS pharmacology & translational science

Published: October 24, 2025

Expedient single-round selection of hyper-modified aptamer targeting insulin receptor from over-represented dually nucleobase-modified DNA libraries.

Expedient single-round selection of hyper-modified aptamer targeting insulin receptor from over-represented dually nucleobase-modified DNA libraries.

Journal: Nature communications

Published: October 24, 2025

Hydrophobic alkyl-linked base-modified pyrimidine and 7-deazapurine 2'-deoxyribonucleoside phosphoramidites: synthesis and application in solid-phase synthesis of modified and hypermodified oligonucleotides.

Hydrophobic alkyl-linked base-modified pyrimidine and 7-deazapurine 2'-deoxyribonucleoside phosphoramidites: synthesis and application in solid-phase synthesis of modified and hypermodified oligonucleotides.

Journal: RSC advances

Published: August 19, 2025

Versatile Enzymatic Approach for Truncation, Labeling, and Mutation of Nucleobase-Modified Aptamers Demonstrated on Indole-Modified β-Conglutin Aptamer.

Versatile Enzymatic Approach for Truncation, Labeling, and Mutation of Nucleobase-Modified Aptamers Demonstrated on Indole-Modified β-Conglutin Aptamer.

Journal: Chembiochem : a European journal of chemical biology

Published: July 14, 2025

Super-Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation.

Super-Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: April 02, 2025

Synthesis of 2-Substituted Adenosine Triphosphate Derivatives and their use in Enzymatic Synthesis and Postsynthetic Labelling of RNA.

Synthesis of 2-Substituted Adenosine Triphosphate Derivatives and their use in Enzymatic Synthesis and Postsynthetic Labelling of RNA.

Journal: Chembiochem : a European journal of chemical biology

Published: March 20, 2025

Polymerase Synthesis of Hypermodified DNA Displaying a Combination of Thiol, Hydroxyl, Carboxylate, and Imidazole Functional Groups in the Major Groove.

Polymerase Synthesis of Hypermodified DNA Displaying a Combination of Thiol, Hydroxyl, Carboxylate, and Imidazole Functional Groups in the Major Groove.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)

Published: March 14, 2025

Identification of 6‑Aryl-7-Deazapurine Ribonucleoside Phosphonates as Inhibitors of Ecto-5'-Nucleotidase (CD73).

Identification of 6‑Aryl-7-Deazapurine Ribonucleoside Phosphonates as Inhibitors of Ecto-5'-Nucleotidase (CD73).

Journal: ACS pharmacology & translational science

Published: March 11, 2025

Showing 1-12 of 132

Last Updated: 09/26/2026