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Dr. Micheal P. Siciliano
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Micheal P. Siciliano
Podiatric Medicine
484-337-3000
130 S Bryn Mawr Ave
Bryn Mawr, PA 19010
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Last Updated: 09/26/2026
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Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells.
Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells.
Journal:
Cell reports
Published:
January 16, 2018
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Poly(ADP-ribose) Polymerase 1, PARP1, modifies EZH2 and inhibits EZH2 histone methyltransferase activity after DNA damage.
Poly(ADP-ribose) Polymerase 1, PARP1, modifies EZH2 and inhibits EZH2 histone methyltransferase activity after DNA damage.
Journal:
Oncotarget
Published:
October 06, 2017
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Last Updated: 09/26/2026