Michele Bassi

Parma, Italy

Last Updated: 09/26/2026

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Found 12 publications

Pharmacokinetics and absorption, distribution, metabolism and excretion profiling of tanimilast following an intravenous 14C-microtracer coadministered with an inhaled dose in healthy male individuals.

Pharmacokinetics and absorption, distribution, metabolism and excretion profiling of tanimilast following an intravenous 14C-microtracer coadministered with an inhaled dose in healthy male individuals.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: July 31, 2024

CHF6523 data suggest that the phosphoinositide 3-kinase delta isoform is not a suitable target for the management of COPD.

CHF6523 data suggest that the phosphoinositide 3-kinase delta isoform is not a suitable target for the management of COPD.

Journal: Respiratory research

Published: June 11, 2024

Serum IL-8 as a Determinant of Response to Phosphodiesterase-4 Inhibition in Chronic Obstructive Pulmonary Disease.

Serum IL-8 as a Determinant of Response to Phosphodiesterase-4 Inhibition in Chronic Obstructive Pulmonary Disease.

Journal: American journal of respiratory and critical care medicine

Published: May 16, 2023

A Novel Processing-Free Method for RNAseq Analysis of Spontaneous Sputum in Chronic Obstructive Pulmonary Disease.

A Novel Processing-Free Method for RNAseq Analysis of Spontaneous Sputum in Chronic Obstructive Pulmonary Disease.

Journal: Frontiers in pharmacology

Published: May 04, 2021

COPD patients with chronic bronchitis and higher sputum eosinophil counts show increased type-2 and PDE4 gene expression in sputum.

COPD patients with chronic bronchitis and higher sputum eosinophil counts show increased type-2 and PDE4 gene expression in sputum.

Journal: Journal of cellular and molecular medicine

Published: September 26, 2020

Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines.

Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines.

Journal: Journal of medicinal chemistry

Published: November 13, 2019

Sputum and blood transcriptomics characterisation of the inhaled PDE4 inhibitor CHF6001 on top of triple therapy in patients with chronic bronchitis.

Sputum and blood transcriptomics characterisation of the inhaled PDE4 inhibitor CHF6001 on top of triple therapy in patients with chronic bronchitis.

Journal: Respiratory research

Published: October 17, 2019

Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL.

Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL.

Journal: Scientific reports

Published: April 06, 2016

Amino Acid Derivatives as Palmitoylethanolamide Prodrugs: Synthesis, In Vitro Metabolism and In Vivo Plasma Profile in Rats.

Amino Acid Derivatives as Palmitoylethanolamide Prodrugs: Synthesis, In Vitro Metabolism and In Vivo Plasma Profile in Rats.

Journal: PloS one

Published: March 12, 2015

Predicting the reactivity of nitrile-carrying compounds with cysteine: a combined computational and experimental study.

Predicting the reactivity of nitrile-carrying compounds with cysteine: a combined computational and experimental study.

Journal: ACS medicinal chemistry letters

Published: November 28, 2013

Long-lasting inhibition of EGFR autophosphorylation in A549 tumor cells by intracellular accumulation of non-covalent inhibitors.

Long-lasting inhibition of EGFR autophosphorylation in A549 tumor cells by intracellular accumulation of non-covalent inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: June 14, 2013

Arginine clustering on calix[4]arene macrocycles for improved cell penetration and DNA delivery.

Arginine clustering on calix[4]arene macrocycles for improved cell penetration and DNA delivery.

Journal: Nature communications

Published: January 25, 2013

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Last Updated: 09/26/2026