Mihiro Sunose

BioCity, Pennyfoot Street, U.K
Nottingham, ENG NG11GF, United Kingdom

Last Updated: 09/26/2026

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Found 10 publications

Discovery of Potent and Orally Bioavailable Novel Cluster of Differentiation 38 (CD38) Small Molecule Inhibitors.

Discovery of Potent and Orally Bioavailable Novel Cluster of Differentiation 38 (CD38) Small Molecule Inhibitors.

Journal: Journal of medicinal chemistry

Published: May 25, 2026

The bactericidal FabI inhibitor Debio 1453 clears antibiotic-resistant Neisseria gonorrhoeae infection in vivo.

The bactericidal FabI inhibitor Debio 1453 clears antibiotic-resistant Neisseria gonorrhoeae infection in vivo.

Journal: Nature communications

Published: December 19, 2023

Structure-activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling.

Structure-activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling.

Journal: Scientific reports

Published: November 21, 2023

Asymmetrically Substituted Quadruplex-Binding Naphthalene Diimide Showing Potent Activity in Pancreatic Cancer Models.

Asymmetrically Substituted Quadruplex-Binding Naphthalene Diimide Showing Potent Activity in Pancreatic Cancer Models.

Journal: ACS medicinal chemistry letters

Published: June 09, 2020

In Vitro and In Vivo Efficacy of a Novel and Long-Acting Fungicidal Azole, PC1244, on Aspergillus fumigatus Infection.

In Vitro and In Vivo Efficacy of a Novel and Long-Acting Fungicidal Azole, PC1244, on Aspergillus fumigatus Infection.

Journal: Antimicrobial agents and chemotherapy

Published: September 15, 2017

In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection.

In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection.

Journal: Antimicrobial agents and chemotherapy

Published: October 24, 2016

CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model.

CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model.

Journal: ACS medicinal chemistry letters

Published: April 08, 2016

Discovery of novel PI3Kγ/δ inhibitors as potential agents for inflammation.

Discovery of novel PI3Kγ/δ inhibitors as potential agents for inflammation.

Journal: Bioorganic & medicinal chemistry letters

Published: May 08, 2012

SAR studies around a series of triazolopyridines as potent and selective PI3Kγ inhibitors.

SAR studies around a series of triazolopyridines as potent and selective PI3Kγ inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: May 04, 2012

Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.

Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.

Journal: Bioorganic & medicinal chemistry letters

Published: May 04, 2012

Showing 1-10 of 10

Last Updated: 09/26/2026