Mikhail V. Shepelev

34/5 Vavilova Str
Moscow, MOW 119334, Russian Federation

Last Updated: 09/26/2026

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Found 29 publications

The Chimeric Nuclease SpRYc Exhibits Highly Variable Performance Across Biological Systems.

The Chimeric Nuclease SpRYc Exhibits Highly Variable Performance Across Biological Systems.

Journal: International journal of molecular sciences

Published: December 20, 2025

Production of virus-like particles with AsCas12a nuclease and CMV-driven crRNA for mammalian genome editing.

Production of virus-like particles with AsCas12a nuclease and CMV-driven crRNA for mammalian genome editing.

Journal: Frontiers in genome editing

Published: October 29, 2025

WBSCR Locus: At the Crossroads of Human Behavioral Disorders and Domestication of Animals.

WBSCR Locus: At the Crossroads of Human Behavioral Disorders and Domestication of Animals.

Journal: International journal of molecular sciences

Published: July 29, 2025

A Novel Mechanism for Transcription Termination in the mod(mdg4) Locus of Drosophila melanogaster.

A Novel Mechanism for Transcription Termination in the mod(mdg4) Locus of Drosophila melanogaster.

Journal: Biology

Published: November 05, 2024

Efficient Genome Editing Using 'NanoMEDIC' AsCas12a-VLPs Produced with Pol II-Transcribed crRNA.

Efficient Genome Editing Using 'NanoMEDIC' AsCas12a-VLPs Produced with Pol II-Transcribed crRNA.

Journal: International journal of molecular sciences

Published: November 02, 2024

A New Chimeric Antibody against the HIV-1 Fusion Inhibitory Peptide MT-C34 with a High Affinity and Fc-Mediated Cellular Cytotoxicity.

A New Chimeric Antibody against the HIV-1 Fusion Inhibitory Peptide MT-C34 with a High Affinity and Fc-Mediated Cellular Cytotoxicity.

Journal: Biology

Published: August 01, 2024

Generation of LEPR Knockout Rabbits with CRISPR/CAS9 System.

Generation of LEPR Knockout Rabbits with CRISPR/CAS9 System.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections

Published: May 25, 2024

Increasing Gene Editing Efficiency via CRISPR/Cas9- or Cas12a-Mediated Knock-In in Primary Human T Cells.

Increasing Gene Editing Efficiency via CRISPR/Cas9- or Cas12a-Mediated Knock-In in Primary Human T Cells.

Journal: Biomedicines

Published: November 27, 2023

The RRE-Rev Module Has No Effect on the Packaging Efficiency of Cas9 and Gag Proteins into NanoMEDIC Virus-like Particles.

The RRE-Rev Module Has No Effect on the Packaging Efficiency of Cas9 and Gag Proteins into NanoMEDIC Virus-like Particles.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections

Published: November 22, 2023

Advances of Genome Editing with CRISPR/Cas9 in Neurodegeneration: The Right Path towards Therapy.

Advances of Genome Editing with CRISPR/Cas9 in Neurodegeneration: The Right Path towards Therapy.

Journal: Biomedicines

Published: November 08, 2023

Donor DNA Modification with Cas9 Targeting Sites Improves the Efficiency of MTC34 Knock-in into the CXCR4 Locus

Donor DNA Modification with Cas9 Targeting Sites Improves the Efficiency of MTC34 Knock-in into the CXCR4 Locus

Journal: Molekuliarnaia biologiia

Published: November 03, 2023

Methods to Increase the Efficiency of Knock-in of a Construct Encoding the HIV-1 Fusion Inhibitor, MT-C34 Peptide, into the CXCR4 Locus in the CEM/R5 T Cell Line

Methods to Increase the Efficiency of Knock-in of a Construct Encoding the HIV-1 Fusion Inhibitor, MT-C34 Peptide, into the CXCR4 Locus in the CEM/R5 T Cell Line

Journal: Molekuliarnaia biologiia

Published: October 31, 2023

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Last Updated: 09/26/2026