Mikko T. Holmberg
Helsinki, Finland
Last Updated: 09/26/2026
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Found 9 publications
Ticagrelor Increases Exposure to the Breast Cancer Resistance Protein Substrate Rosuvastatin.
Journal: Clinical pharmacology and therapeutics
Published: August 04, 2023
CYP3A4*22 Impairs the Elimination of Ticagrelor, But Has No Significant Effect on the Bioactivation of Clopidogrel or Prasugrel.
Journal: Clinical pharmacology and therapeutics
Published: March 19, 2018
Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions .
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: August 21, 2017
Effects of Genetic Variants on Carboxylesterase 1 Gene Expression, and Clopidogrel Pharmacokinetics and Antiplatelet Effects.
Journal: Basic & clinical pharmacology & toxicology
Published: June 21, 2017
Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril.
Journal: British journal of clinical pharmacology
Published: February 06, 2015
Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans.
Journal: Clinical pharmacology and therapeutics
Published: November 03, 2014
Effect of grapefruit juice on the bioactivation of prasugrel.
Journal: British journal of clinical pharmacology
Published: October 24, 2014
Grapefruit juice inhibits the metabolic activation of clopidogrel.
Journal: Clinical pharmacology and therapeutics
Published: July 31, 2013
Grapefruit juice markedly increases the plasma concentrations and antiplatelet effects of ticagrelor in healthy subjects.
Journal: British journal of clinical pharmacology
Published: September 29, 2012
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Last Updated: 09/26/2026