Minghua Wang

Chinese Academy Of Medical Sciences & Peking Union Medical College
Beijing, 100050, China

Last Updated: 09/26/2026

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Found 38 publications

Design, synthesis and antibacterial activity of novel LpxC inhibitors containing 1,2,3-triazole moieties.

Design, synthesis and antibacterial activity of novel LpxC inhibitors containing 1,2,3-triazole moieties.

Journal: Bioorganic & medicinal chemistry letters

Published: January 05, 2026

Design, Synthesis, and Biological Evaluation of Novel Core Scaffold-Modified HIV-1 Protease Inhibitors for Overcoming Drug Resistance.

Design, Synthesis, and Biological Evaluation of Novel Core Scaffold-Modified HIV-1 Protease Inhibitors for Overcoming Drug Resistance.

Journal: Journal of medicinal chemistry

Published: October 22, 2025

Fluorescent probe-based detection of outer membrane damage of Gram-negative bacteria.

Fluorescent probe-based detection of outer membrane damage of Gram-negative bacteria.

Journal: SLAS discovery : advancing life sciences R & D

Published: August 28, 2025

Rational design, synthesis, and evaluating primary biological activities of novel HIV-1 protease inhibitors containing heteraryl acetamides as the P2 ligands.

Rational design, synthesis, and evaluating primary biological activities of novel HIV-1 protease inhibitors containing heteraryl acetamides as the P2 ligands.

Journal: Bioorganic & medicinal chemistry

Published: May 21, 2025

Novel Oxazolidinone Derivatives Containing Quaternary Ammonium Fragments with Potent Antibacterial Potency.

Novel Oxazolidinone Derivatives Containing Quaternary Ammonium Fragments with Potent Antibacterial Potency.

Journal: ACS medicinal chemistry letters

Published: May 21, 2025

A Donor-Acceptor Covalent Triazine Framework-based "On-Off-On" Electrochemiluminescence Aptasensor for Detecting Aflatoxin B1 with the Assistance of Nicking Endonuclease-powered DNA Walking Machine.

A Donor-Acceptor Covalent Triazine Framework-based "On-Off-On" Electrochemiluminescence Aptasensor for Detecting Aflatoxin B1 with the Assistance of Nicking Endonuclease-powered DNA Walking Machine.

Journal: Langmuir : the ACS journal of surfaces and colloids

Published: April 15, 2025

Discovery and rational optimization of 2, 2'-((1H-indole-2,3-diyl) bis (thio))diacetamide as novel SARS-CoV-2 RdRp inhibitors.

Discovery and rational optimization of 2, 2'-((1H-indole-2,3-diyl) bis (thio))diacetamide as novel SARS-CoV-2 RdRp inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: January 02, 2025

Synthesis and biological evaluation of substituted quinolines containing piperazine moieties against Influenza A virus.

Synthesis and biological evaluation of substituted quinolines containing piperazine moieties against Influenza A virus.

Journal: Bioorganic & medicinal chemistry letters

Published: July 23, 2024

A dual-photoelectrode fuel cell-driven self-powered aptasensor based on the 1D/2D In2S3/MoS2@Fe-CNTs heterojunction for the ultrasensitive detection of Staphylococcus aureus.

A dual-photoelectrode fuel cell-driven self-powered aptasensor based on the 1D/2D In2S3/MoS2@Fe-CNTs heterojunction for the ultrasensitive detection of Staphylococcus aureus.

Journal: Analytica chimica acta

Published: March 16, 2023

Discovery and development of benzene sulfonamide derivatives as anti-hepatic fibrosis agents.

Discovery and development of benzene sulfonamide derivatives as anti-hepatic fibrosis agents.

Journal: Bioorganic & medicinal chemistry letters

Published: January 28, 2023

Design, synthesis, and biological evaluation of novel HIV-1 protease inhibitors containing pyrrolidine-derived P2 ligands to combat drug-resistant variant.

Design, synthesis, and biological evaluation of novel HIV-1 protease inhibitors containing pyrrolidine-derived P2 ligands to combat drug-resistant variant.

Journal: European journal of medicinal chemistry

Published: January 04, 2023

Defective porphyrin-based metal-organic framework nanosheets derived from V2CTx MXene as a robust bioplatform for impedimetric aptasensing 17β-estradiol.

Defective porphyrin-based metal-organic framework nanosheets derived from V2CTx MXene as a robust bioplatform for impedimetric aptasensing 17β-estradiol.

Journal: Food chemistry

Published: November 30, 2022

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Last Updated: 09/26/2026