Minghui L. Tong

103 Wenhua Road
Shenyang, 110016, China

Last Updated: 09/26/2026

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Found 46 publications

Discovery of ZSL-M028: A Potent, Selective and Orally Available Quinazoline-Based PLK4 Inhibitor Targeting TRIM37-Amplified Neuroblastoma.

Discovery of ZSL-M028: A Potent, Selective and Orally Available Quinazoline-Based PLK4 Inhibitor Targeting TRIM37-Amplified Neuroblastoma.

Journal: Journal of medicinal chemistry
Published: July 16, 2026

Identification of 2,4-Diaminopyrimidine Derivatives as Novel Gut-Restricted Selective JAK1 Inhibitors for the Treatment of Inflammatory Bowel Disease.

Identification of 2,4-Diaminopyrimidine Derivatives as Novel Gut-Restricted Selective JAK1 Inhibitors for the Treatment of Inflammatory Bowel Disease.

Journal: Journal of medicinal chemistry
Published: February 24, 2026

Design, synthesis, and evaluation of dual-target inhibitors of acetylcholinesterase (AChE) and soluble epoxide hydrolase (sEH) for the treatment of Alzheimer's disease.

Design, synthesis, and evaluation of dual-target inhibitors of acetylcholinesterase (AChE) and soluble epoxide hydrolase (sEH) for the treatment of Alzheimer's disease.

Journal: European journal of medicinal chemistry
Published: February 12, 2026

Discovery of Tetrazolone derivatives as potent PPARα/δ dual agonists for metabolic dysfunction-associated steatohepatitis.

Discovery of Tetrazolone derivatives as potent PPARα/δ dual agonists for metabolic dysfunction-associated steatohepatitis.

Journal: Bioorganic chemistry
Published: January 31, 2026

One case of VV-ECMO treatment for dimethyl sulfate poisoning

One case of VV-ECMO treatment for dimethyl sulfate poisoning

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
Published: December 03, 2025

Discovery of potent TNIK inhibitors containing a 1H-pyrrolo[2,3-b]pyridine scaffold as promising therapeutics for colorectal cancer.

Discovery of potent TNIK inhibitors containing a 1H-pyrrolo[2,3-b]pyridine scaffold as promising therapeutics for colorectal cancer.

Journal: European journal of medicinal chemistry
Published: December 03, 2025

Hydrocolloid versus Liquid Dressings for Incontinence-Associated Dermatitis: A Clinical Evaluation in Critically Ill Patients.

Hydrocolloid versus Liquid Dressings for Incontinence-Associated Dermatitis: A Clinical Evaluation in Critically Ill Patients.

Journal: Clinical, cosmetic and investigational dermatology
Published: September 26, 2025

Effect of a checklist-based core competency training and evaluation system on work-related alienation among critical care nurses.

Effect of a checklist-based core competency training and evaluation system on work-related alienation among critical care nurses.

Journal: Frontiers in public health
Published: September 19, 2025

Multiparameter Optimization of Broad-Spectrum Antibacterial Activity, ADMET Properties, and MAO-A/B Inhibition of Novel Biaryloxazolidinone-Hydrazone Derivatives: Identification of a Lead with In Vivo Efficacy against Linezolid-Resistant Staphylococcus aureus.

Multiparameter Optimization of Broad-Spectrum Antibacterial Activity, ADMET Properties, and MAO-A/B Inhibition of Novel Biaryloxazolidinone-Hydrazone Derivatives: Identification of a Lead with In Vivo Efficacy against Linezolid-Resistant Staphylococcus aureus.

Journal: Journal of medicinal chemistry
Published: August 15, 2025

Design, synthesis, and biological evaluation of indazole-based PLK4 inhibitors.

Design, synthesis, and biological evaluation of indazole-based PLK4 inhibitors.

Journal: RSC medicinal chemistry
Published: July 24, 2025

Design, synthesis, and biological evaluation of 5-chlorine-2-amino-pyrimidine derivatives as potent PLK4 inhibitors.

Design, synthesis, and biological evaluation of 5-chlorine-2-amino-pyrimidine derivatives as potent PLK4 inhibitors.

Journal: RSC medicinal chemistry
Published: May 15, 2025

Rational design of CZL-S092: A novel indazole-based PLK4 inhibitor targeting neuroblastoma through virtual screening and fragment-based drug design strategies.

Rational design of CZL-S092: A novel indazole-based PLK4 inhibitor targeting neuroblastoma through virtual screening and fragment-based drug design strategies.

Journal: European journal of medicinal chemistry
Published: April 27, 2025
Showing 1-12 of 46

Last Updated: 09/26/2026