Mirko Buchholz

Halle, NI, Germany

Last Updated: 09/26/2026

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Found 27 publications

Effect of a bacterial glutaminyl cyclase inhibitor on multi-species-biofilms.

Effect of a bacterial glutaminyl cyclase inhibitor on multi-species-biofilms.

Journal: Frontiers in oral health

Published: September 30, 2025

Novel small molecule targeting PgQC reduces Porphyromonas gingivalis virulence.

Novel small molecule targeting PgQC reduces Porphyromonas gingivalis virulence.

Journal: Frontiers in oral health

Published: September 30, 2025

Preclinical Validation of MIN-T: A Novel Controlled-Released Formulation for the Adjunctive Local Application of Minocycline in Periodontitis.

Preclinical Validation of MIN-T: A Novel Controlled-Released Formulation for the Adjunctive Local Application of Minocycline in Periodontitis.

Journal: Antibiotics (Basel, Switzerland)

Published: August 30, 2024

Synthesis and structure-activity relationships of pyrazole-based inhibitors of meprin α and β.

Synthesis and structure-activity relationships of pyrazole-based inhibitors of meprin α and β.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: January 20, 2023

Synthesis and structure-activity relationships of USP48 deubiquitinylase inhibitors.

Synthesis and structure-activity relationships of USP48 deubiquitinylase inhibitors.

Journal: Archiv der Pharmazie

Published: December 22, 2022

Identification and evaluation of a novel tribenzamide derivative as an inhibitor targeting the entry of the respiratory syncytial virus.

Identification and evaluation of a novel tribenzamide derivative as an inhibitor targeting the entry of the respiratory syncytial virus.

Journal: Antiviral research

Published: November 14, 2022

Tetrahydroimidazo[4,5-c]pyridine-Based Inhibitors of Porphyromonas gingivalis Glutaminyl Cyclase.

Tetrahydroimidazo[4,5-c]pyridine-Based Inhibitors of Porphyromonas gingivalis Glutaminyl Cyclase.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: October 15, 2021

Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis.

Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis.

Journal: The Journal of biological chemistry

Published: November 19, 2020

Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold-Hopping Approach.

Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold-Hopping Approach.

Journal: ChemMedChem

Published: October 20, 2020

Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease.

Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease.

Journal: Biochemistry

Published: June 20, 2020

A Primary Evaluation of Potential Small-Molecule Inhibitors of the Astacin Metalloproteinase Ovastacin, a Novel Drug Target in Female Infertility Treatment.

A Primary Evaluation of Potential Small-Molecule Inhibitors of the Astacin Metalloproteinase Ovastacin, a Novel Drug Target in Female Infertility Treatment.

Journal: ChemMedChem

Published: June 08, 2020

Controlled release minocycline-lipid-complex extrudates for the therapy of periodontitis with enhanced flexibility.

Controlled release minocycline-lipid-complex extrudates for the therapy of periodontitis with enhanced flexibility.

Journal: International journal of pharmaceutics

Published: April 21, 2020

Showing 1-12 of 27

Last Updated: 09/26/2026