Miroslav Perina

Olomouc, Czech Republic

Last Updated: 09/26/2026

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Found 26 publications

Correction: Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity.

Correction: Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity.

Journal: Frontiers in pharmacology

Published: May 30, 2026

Structure-guided identification and characterization of a novel pyrazolo[1,5-a]pyrimidine ligand of SARS-CoV-2 main protease.

Structure-guided identification and characterization of a novel pyrazolo[1,5-a]pyrimidine ligand of SARS-CoV-2 main protease.

Journal: International journal of biological macromolecules

Published: March 03, 2026

Synthesis, Anthelmintic Activity, and Mechanism of Action of 5-Aryl-1H-indoles.

Synthesis, Anthelmintic Activity, and Mechanism of Action of 5-Aryl-1H-indoles.

Journal: Journal of agricultural and food chemistry

Published: December 16, 2025

Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity.

Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity.

Journal: Frontiers in pharmacology

Published: November 12, 2025

3H-pyrazolo[4,3-f]quinoline hinge binder, a tunable scaffold for development of novel kinase inhibitors against FLT3-driven leukemia.

3H-pyrazolo[4,3-f]quinoline hinge binder, a tunable scaffold for development of novel kinase inhibitors against FLT3-driven leukemia.

Journal: European journal of medicinal chemistry

Published: September 16, 2025

The methioninase from the alkalithermophile Thermobrachium celere possesses suitable properties for treatment of cancer.

The methioninase from the alkalithermophile Thermobrachium celere possesses suitable properties for treatment of cancer.

Journal: International journal of biological macromolecules

Published: July 01, 2025

Isoxazole-Based Compounds Targeting the Taxane-Binding Site of Tubulin.

Isoxazole-Based Compounds Targeting the Taxane-Binding Site of Tubulin.

Journal: Archiv der Pharmazie

Published: February 13, 2025

CDK2-based CDK7 mimic as a tool for structural analysis: Biochemical validation and crystal structure with SY5609.

CDK2-based CDK7 mimic as a tool for structural analysis: Biochemical validation and crystal structure with SY5609.

Journal: International journal of biological macromolecules

Published: September 11, 2024

Identification of furo[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazole derivatives as novel FLT3-ITD inhibitors.

Identification of furo[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazole derivatives as novel FLT3-ITD inhibitors.

Journal: European journal of medicinal chemistry

Published: April 03, 2024

Synthesis and estrogenic activity of BODIPY-labeled estradiol conjugates.

Synthesis and estrogenic activity of BODIPY-labeled estradiol conjugates.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: March 24, 2024

Targeting the CLK2/SRSF9 splicing axis in prostate cancer leads to decreased ARV7 expression.

Targeting the CLK2/SRSF9 splicing axis in prostate cancer leads to decreased ARV7 expression.

Journal: Molecular oncology

Published: March 13, 2024

Dihydrotestosterone-based A-ring-fused pyridines: Microwave-assisted synthesis and biological evaluation in prostate cancer cells compared to structurally related quinolines.

Dihydrotestosterone-based A-ring-fused pyridines: Microwave-assisted synthesis and biological evaluation in prostate cancer cells compared to structurally related quinolines.

Journal: The Journal of steroid biochemistry and molecular biology

Published: March 07, 2023

Showing 1-12 of 26

Last Updated: 09/26/2026