Mitsuhiko Ikura
Toronto, ON M5G1L7, Canada
Last Updated: 09/26/2026
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Found 91 publications
CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk.
Journal: Nature communications
Published: February 17, 2026
CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk.
Journal: Nature communications
Published: February 17, 2026
Allosteric targeting of the ACE2 dimer interface by a medium-sized compound inhibits SARS-CoV-2 entry.
Journal: Journal of molecular biology
Published: February 11, 2026
Erythrocytosis-inducing PHD2 mutations implicate biological role for N-terminal prolyl-hydroxylation in HIF1α oxygen-dependent degradation domain.
Journal: eLife
Published: October 20, 2025
CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk.
Journal: bioRxiv : the preprint server for biology
Published: August 06, 2025
Switch II Pocket Inhibitor Allosterically Freezes KRASG12D Nucleotide-binding Site and Arrests the GTPase Cycle.
Journal: Journal of molecular biology
Published: February 17, 2025
DIRAS3-derived cyclic peptides disrupt KRAS-RAF interaction and KRAS nanoclustering, suppressing KRAS-driven pancreatic and ovarian tumors.
Journal: iScience
Published: January 21, 2025
Time-resolved NMR detection of prolyl-hydroxylation in intrinsically disordered region of HIF-1α.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: September 04, 2024
Crystal structure of NRAS Q61K with a ligand-induced pocket near switch II.
Journal: European journal of cell biology
Published: January 17, 2024
Reconstitution and characterization of BRAF in complex with 14-3-3 and KRAS4B on nanodiscs.
Journal: Protein science : a publication of the Protein Society
Published: December 21, 2023
Aromatically stacking the odds in favour of increased ORAI1 activation.
Journal: Cell calcium
Published: December 15, 2023
Biochemical and biophysical characterization of the RAS family small GTPase protein DiRAS3.
Journal: Protein expression and purification
Published: July 25, 2023
Last Updated: 09/26/2026