Moataz A. Shaldam

Kafr Ash Shaykh, SHR 33516, Egypt

Last Updated: 09/26/2026

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Found 84 publications

Design and synthesis of 1,3,4-oxadiazole-tethered N-substituted isatin hybrids as SARS-CoV-2 main protease inhibitors: biological evaluation, kinetic investigation, and in silico studies.

Design and synthesis of 1,3,4-oxadiazole-tethered N-substituted isatin hybrids as SARS-CoV-2 main protease inhibitors: biological evaluation, kinetic investigation, and in silico studies.

Journal: RSC advances

Published: July 04, 2026

Mutant isocitrate dehydrogenase in cancer: Structural biology, small-molecule inhibitors, and future drug discovery strategies.

Mutant isocitrate dehydrogenase in cancer: Structural biology, small-molecule inhibitors, and future drug discovery strategies.

Journal: Drug discovery today

Published: June 22, 2026

Correction: Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity.

Correction: Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity.

Journal: Frontiers in pharmacology

Published: May 30, 2026

Synthesis, Antibacterial Evaluation, and Chemometric Profiling of a Vanilloid-Based Compounds Library Active Against Helicobacter pylori.

Synthesis, Antibacterial Evaluation, and Chemometric Profiling of a Vanilloid-Based Compounds Library Active Against Helicobacter pylori.

Journal: Antibiotics (Basel, Switzerland)

Published: May 21, 2026

Biotransformation-guided production of quinalizarin as an antibacterial agent against Acinetobacter baumannii.

Biotransformation-guided production of quinalizarin as an antibacterial agent against Acinetobacter baumannii.

Journal: Applied microbiology and biotechnology

Published: May 08, 2026

Identification of Quinoline Tethered Thiadiazole/Thiazole Derivatives as Potent Tyrosinase Inhibitors With Promising Anti-Toxoplasma gondii Agents: Design, Synthesis, and Computational Analysis.

Identification of Quinoline Tethered Thiadiazole/Thiazole Derivatives as Potent Tyrosinase Inhibitors With Promising Anti-Toxoplasma gondii Agents: Design, Synthesis, and Computational Analysis.

Journal: Drug development research

Published: April 11, 2026

Molecular Boomerangs Against Cancer: Design, Synthesis, Biological Evaluation, and In Silico Study of Novel Dual PARP-1/EGFR Inhibitors.

Molecular Boomerangs Against Cancer: Design, Synthesis, Biological Evaluation, and In Silico Study of Novel Dual PARP-1/EGFR Inhibitors.

Journal: Drug development research

Published: March 26, 2026

Patents involving monoamine oxidase (MAO): a comprehensive update (2022-2025) on its inhibitors and applications.

Patents involving monoamine oxidase (MAO): a comprehensive update (2022-2025) on its inhibitors and applications.

Journal: Expert opinion on therapeutic patents

Published: February 16, 2026

Thiazole-Semicarbazone Hybrids as Dual-Stage Inhibitors of Leishmania major Growth: Design, Synthesis, and Mechanistic Insights.

Thiazole-Semicarbazone Hybrids as Dual-Stage Inhibitors of Leishmania major Growth: Design, Synthesis, and Mechanistic Insights.

Journal: Drug development research

Published: January 12, 2026

Biphenyl urea derivatives as novel GPX4 inhibitors: ferroptosis-mediated antiproliferative activity against CNS cancer cells.

Biphenyl urea derivatives as novel GPX4 inhibitors: ferroptosis-mediated antiproliferative activity against CNS cancer cells.

Journal: Bioorganic chemistry

Published: January 05, 2026

Isatin-triazole/imidazole hybrids as dual CDK2/VEGFR2 inhibitors with potent anti-cancer activity: design, synthesis, and biological evaluations.

Isatin-triazole/imidazole hybrids as dual CDK2/VEGFR2 inhibitors with potent anti-cancer activity: design, synthesis, and biological evaluations.

Journal: Bioorganic chemistry

Published: December 11, 2025

Design, synthesis, in vitro, and in silico evaluation of multi-functionalized pyrimidines as potential multitarget-directed anti-inflammatory agents.

Design, synthesis, in vitro, and in silico evaluation of multi-functionalized pyrimidines as potential multitarget-directed anti-inflammatory agents.

Journal: Bioorganic chemistry

Published: November 28, 2025

Showing 1-12 of 84

Last Updated: 09/26/2026