Mohamed Aziz-Abdel

Al Minya, MN 61768, Egypt

Last Updated: 09/26/2026

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Found 71 publications

Harnessing Substituted 4-Chlorothieno[2,3-b]pyridine as a New Cap for Potent and Selective Antiproliferative HDAC Inhibitors.

Harnessing Substituted 4-Chlorothieno[2,3-b]pyridine as a New Cap for Potent and Selective Antiproliferative HDAC Inhibitors.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: February 12, 2026

Phenylpiperazine/dithioates as novel H2S donors: design, synthesis, H2S release, formulation as PEG-niosomes and antifungal activity against Candida albicans.

Phenylpiperazine/dithioates as novel H2S donors: design, synthesis, H2S release, formulation as PEG-niosomes and antifungal activity against Candida albicans.

Journal: Bioorganic chemistry

Published: November 20, 2025

Ferroptosis-Driven Anticancer Activity of 1,3,4-Oxadiazole-Benzimidazole/Acetamide Hybrids: Design, Synthesis, and Biological Profiling.

Ferroptosis-Driven Anticancer Activity of 1,3,4-Oxadiazole-Benzimidazole/Acetamide Hybrids: Design, Synthesis, and Biological Profiling.

Journal: Archiv der Pharmazie

Published: September 06, 2025

Novel pyrazole-oxadiazole-chalcone/oxime hybrids as dual EGFR/VEGFR-2 inhibitors with promising anticancer potential: a comprehensive cytotoxicity evaluation, mechanistic insights and SAR analysis.

Novel pyrazole-oxadiazole-chalcone/oxime hybrids as dual EGFR/VEGFR-2 inhibitors with promising anticancer potential: a comprehensive cytotoxicity evaluation, mechanistic insights and SAR analysis.

Journal: Molecular diversity

Published: September 04, 2025

Rational design of 2-substituted thio-7-chloroquinazolin-4(3H)-one derivatives as dual EGFR/VEGFR-2 inhibitors with broad-Spectrum anticancer and apoptotic activities.

Rational design of 2-substituted thio-7-chloroquinazolin-4(3H)-one derivatives as dual EGFR/VEGFR-2 inhibitors with broad-Spectrum anticancer and apoptotic activities.

Journal: Bioorganic chemistry

Published: August 21, 2025

Biologically Active Benzimidazole Hybrids as Cancer Therapeutics: Recent Advances.

Biologically Active Benzimidazole Hybrids as Cancer Therapeutics: Recent Advances.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: August 13, 2025

Design, Synthesis, and Biological Evaluation of Novel Benzimidazole/Schiff Base Hybrid Derivatives With Potential Biological Activities.

Design, Synthesis, and Biological Evaluation of Novel Benzimidazole/Schiff Base Hybrid Derivatives With Potential Biological Activities.

Journal: Archiv der Pharmazie

Published: August 05, 2025

Design, synthesis, and biological evaluation of novel 1,5-diarylpyrazole carboxamides with dual inhibition of EGFR and COX-2 for the treatment of cancer and inflammatory diseases.

Design, synthesis, and biological evaluation of novel 1,5-diarylpyrazole carboxamides with dual inhibition of EGFR and COX-2 for the treatment of cancer and inflammatory diseases.

Journal: Bioorganic & medicinal chemistry letters

Published: July 17, 2025

Design, Synthesis, and In Vitro Anticancer Evaluation of Thiazole-Based Chalcones Linked to Sulfanilamide as Tumor-Associated Carbonic Anhydrase IX and XII Inhibitors.

Design, Synthesis, and In Vitro Anticancer Evaluation of Thiazole-Based Chalcones Linked to Sulfanilamide as Tumor-Associated Carbonic Anhydrase IX and XII Inhibitors.

Journal: Journal of medicinal chemistry

Published: July 07, 2025

Targeting melanoma resistance: Novel oxindole and non-oxindole-based benzimidazole derivatives as potent dual inhibitors of BRAFV600E and ABL2 kinases.

Targeting melanoma resistance: Novel oxindole and non-oxindole-based benzimidazole derivatives as potent dual inhibitors of BRAFV600E and ABL2 kinases.

Journal: European journal of medicinal chemistry

Published: June 17, 2025

Unveiling ortho-phenolic Mannich ciprofloxacin-chalcone conjugates with potential antineoplastic activity: synthesis, mechanistic study, in silico docking and molecular dynamic simulation.

Unveiling ortho-phenolic Mannich ciprofloxacin-chalcone conjugates with potential antineoplastic activity: synthesis, mechanistic study, in silico docking and molecular dynamic simulation.

Journal: European journal of medicinal chemistry

Published: April 22, 2025

Amide linked chalcone derivatives, a promising class of compounds with versatile biological effects.

Amide linked chalcone derivatives, a promising class of compounds with versatile biological effects.

Journal: RSC advances

Published: February 04, 2025

Showing 1-12 of 71

Last Updated: 09/26/2026