Mohamed E. Shaker
Al Mansurah, DK 35516, Egypt
Last Updated: 09/26/2026
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Found 43 publications
Design, synthesis and antiproliferative, apoptotic, and immunomodulatory properties of new heteroaryl pyridine-linked 1,2,4-oxadiazoles as prospective dual EGFR/BRAFV600E inhibitors.
Journal: RSC advances
Published: January 08, 2026
The novel Bruton tyrosine kinase inhibitor branebrutinib abrogates lipopolysaccharide/galactosamine-induced hepatic injury via limiting inflammation and oxidative stress.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: May 20, 2025
Design, synthesis, and apoptotic antiproliferative efficacy of new quinazoline/1,3,4-oxadiazole-2-thione derived EGFR/HER-2 dual inhibitors with anti-breast cancer activity.
Journal: RSC medicinal chemistry
Published: May 20, 2025
Targeting amyloid β42 aggregation using a structurally defined graphene quantum dot model: A combined molecular and biological investigation.
Journal: International journal of biological macromolecules
Published: March 30, 2025
Design, synthesis, and biological investigation of new thiazole-based derivatives as multi-targeted inhibitors endowed with antiproliferative, antioxidant, and antibacterial properties.
Journal: Frontiers in chemistry
Published: March 19, 2025
Corrigendum: Unveiling the therapeutic potential of exogenous β-hydroxybutyrate for chronic colitis in rats: novel insights on autophagy, apoptosis, and pyroptosis.
Journal: Frontiers in pharmacology
Published: February 05, 2024
Design and construction of novel pyridine-pyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox studies.
Journal: Journal of biomolecular structure & dynamics
Published: December 28, 2023
Corrigendum: Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib.
Journal: Frontiers in pharmacology
Published: August 22, 2023
Assembling a Cinnamyl Pharmacophore in the C3-Position of Substituted Isatins via Microwave-Assisted Synthesis: Development of a New Class of Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease.
Journal: Molecules (Basel, Switzerland)
Published: July 19, 2023
Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib.
Journal: Frontiers in pharmacology
Published: April 26, 2023
Emerging roles of tyrosine kinases in hepatic inflammatory diseases and therapeutic opportunities.
Journal: International immunopharmacology
Published: March 10, 2023
The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations.
Journal: Journal of biomolecular structure & dynamics
Published: January 20, 2023
Last Updated: 09/26/2026